4 completed, 1 recruiting. 3 Phase 4, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 3 | Completed 2, Recruiting 1 |
| Phase 1 | 2 | Completed 2 |
Follow trimethobenzamide: new trials by email Literature Review of trimethobenzamide trials Research Report on trimethobenzamide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study to Assess Safety and Tolerability of KarXT With Administration of Antiemetics in Healthy Volunteers KarXT, Trimethobenzamide, Ondansetron - Healthy Volunteers | Phase 4 | Recruiting | Karuna Therapeutics, Inc., a Bristol Myers Squibb company | 180 | 2026-09-03 | 2026-10-15 |
| A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of PF-06649751 in Subjects With Idiopathic Parkinson's Disease PF-06649751, Trimethobenzamide Hydrochloride, Placebo - Idiopathic Parkinson Disease | Phase 1 | Completed | Pfizer | 18 | 2015-03-01 | 2023-09-22 |
| A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of PF-06649751 Co-administered With Trimethobenzamide Hydrochloride in Healthy Subjects PF-06649751, Trimethobenzamide Hydrochloride - Healthy | Phase 1 | Completed | Pfizer | 9 | 2014-11-01 | 2015-01-14 |
| Apokyn for Motor IMProvement of Morning AKinesia Trial (AM IMPAKT) APOKYN, L-dopa, Trimethobenzamide - Parkinson's Disease, Motor Symptoms | Phase 4 | Completed | MDD US Operations, LLC a subsidiary of Supernus Pharmaceuticals | 127 | 2012-12-01 | 2023-08-14 |
| Safety/Efficacy of Tigan® to Control Nausea/Vomiting Experienced During Apokyn® Initiation and Treatment Tigan®, Placebo - Parkinson's Disease | Phase 4 | Completed | Ipsen | 117 | 2007-05-01 | 2019-01-30 |
Parkinson Disease (3) · Nausea (2) · Vomiting (2) · Movement Disorders (1)
Pfizer (2) · Ipsen (1) · Karuna Therapeutics, Inc., a Bristol Myers Squibb company (1) · MDD US Operations, LLC a subsidiary of Supernus Pharmaceuticals (1)
United States (4) · Belgium (2)
Constantino Kantaridis, MD (1) · Gianpiera H. Ceresoli-Borroni, PhD (1)
2014 (2)