3 completed, 2 not yet recruiting, 2 terminated, 1 recruiting. 3 Phase 2, 2 Not applicable, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 1, Not yet recruiting 1, Terminated 1 |
| Not applicable | 2 | Recruiting 1, Terminated 1 |
| Phase 3 | 1 | Completed 1 |
| Phase 4 | 1 | Not yet recruiting 1 |
Follow Total Mesorectal Excision (TME): new trials by email Literature Review of Total Mesorectal Excision (TME) trials Research Report on Total Mesorectal Excision (TME)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Brachytherapy Followed by Nivolumab Prior to Surgery in Rectal Cancer Nivolumab, HDRBET, Total Mesorectal Excision (TME) - Locally Advanced Rectal Cancer | Phase 2 | Not yet recruiting | Dr. Te Vuong | 10 | 2026-07-01 | 2026-06-12 |
| Next Generation STAR-TREC (NG-ST) - Organ Preservation in Early Rectal Cancer Capecitabine + Radiotherapy, Total Mesorectal Excision (TME) - Rectal Cancer | Phase 4 | Not yet recruiting | Vastra Gotaland Region | 90 | 2026-03-12 | 2026-03-19 |
| Organ Preservation First Strategy and Intentional Watch and Wait for MRI Defined Low-risk Rectal Cancer Nonoperative Management (NOM), Local Excision (LE), Total Mesorectal Excision (TME) - Rectal Cancer | Not applicable | Recruiting | Peking University Cancer Hospital & Institute | 96 | 2024-01-17 | 2025-06-12 |
| Comparison Between Tailored Surgery Versus Total Mesorectal Excision in ycT2-3N0M0 Tailored surgery, Total mesorectal excision (TME) - Rectal Cancer, Adenocarcinoma | Not applicable | Terminated | Seoul National University Hospital | 14 | 2022-01-03 | 2024-12-05 |
| Oncological Impact of Lateral Nodes in Rectal Cancer Neoadjuvant chemoradiotherapy (CRT) - Colorectal Adenocarcinoma | Completed | Niguarda Hospital | 317 | 2014-01-01 | 2022-10-25 | |
| Neoadjuvant Radiotherapy Followed by Transanal Endoscopic Microsurgery for T1-T2 Extraperitoneal Rectal Cancer SRT-TEM, LRT-TEM, Transanal Endoscopic Microsurgery (TEM) - RECTAL CANCER | Phase 3 | Completed | European Association for Endoscopic Surgery | 25 | 2011-06-01 | 2018-07-26 |
| Study of Neoadjuvant CT With Selective Radiotherapy in Patients With Intermediate-Risk Cancer Rectum Capecitabine, Oxaliplatin, Bevacizumab - Rectum Cancer | Phase 2 | Completed | Grupo Espanol Multidisciplinario del Cancer Digestivo | 46 | 2009-03-01 | 2013-10-11 |
| Neo-Adjuvant FOLFOX for Rectal Carcinoma FOLFOX, total mesorectal excision (TME) - Rectal Neoplasms | Phase 2 | Terminated | Beth Israel Medical Center | 2 | 2009-01-01 | 2018-03-01 |
Rectal Neoplasms (7)
Beth Israel Medical Center (1) · Dr. Te Vuong (1) · European Association for Endoscopic Surgery (1) · Grupo Espanol Multidisciplinario del Cancer Digestivo (1) · Niguarda Hospital (1) · Peking University Cancer Hospital & Institute (1) · Seoul National University Hospital (1) · Vastra Gotaland Region (1)
Canada (1) · China (1) · Italy (1) · South Korea (1) · Spain (1) · United States (1)
Alberto Arezzo, Assistant Professor of Surgery (1) · Alex Casalots, Pathologist (1) · Ana Darnell, Radiologist (1) · Anna Caltrava, Pathologist (1) · Antonieta Salud, Oncologist (1) · Antonio Lazy, Surgeon (1) · Carles Conill, Radiotherapy (1) · Carles Pericay, Oncologist (1) · Eloy Tejero, Surgeon (1)
2025 (1)