TAK-981: Clinical Trials

6 trials of TAK-981, newest first

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4 terminated, 2 completed. 5 Phase 1, 4 Phase 2, 1 Early Phase 1.

By phase and status

PhaseTrialsStatus
Phase 15Terminated 4, Completed 1
Phase 24Terminated 3, Completed 1
Early Phase 11Completed 1

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Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
An Absorption, Distribution, Metabolism, Excretion (ADME) Study of [14C]Subasumstat in Adults With Advanced or Metastatic Solid Tumors
[14C] Subasumstat, Subasumstat - Solid Tumors
Phase 1TerminatedTakeda32023-11-142025-10-06
A Study Of TAK-981 Given With Monoclonal Antibodies (mAbs) In Adults With Relapsed or Refractory Multiple Myeloma (RRMM)
TAK-981, Mezagitamab, Daratumumab and Hyaluronidase-fihj - Relapsed and/or Refractory Multiple Myeloma (RRMM)
Phase 1 / Phase 2TerminatedTakeda272021-04-202024-10-02
Intratumoral Microdosing of TAK-981 in Head and Neck Cancer
TAK-981, Cetuximab, Avelumab - Head and Neck Cancer
Early Phase 1CompletedPresage Biosciences122020-10-072022-07-29
A Study of TAK-981 Given With Pembrolizumab in Participants With Select Advanced or Metastatic Solid Tumors
TAK-981, Pembrolizumab - Advanced or Metastatic Solid Tumors
Phase 1 / Phase 2CompletedTakeda1612020-08-172025-12-10
A Study of TAK-981 Given With Rituximab in Adults With Relapsed or Refractory CD20-Positive Non-Hodgkin Lymphoma
TAK-981, Rituximab - Lymphoma, Non-Hodgkin
Phase 1 / Phase 2TerminatedTakeda382019-10-152024-06-14
A Study of TAK-981 in People With Advanced Solid Tumors or Cancers in the Immune System
TAK-981 - Neoplasms, Lymphoma
Phase 1 / Phase 2TerminatedTakeda1092018-10-012024-11-19

Conditions studied

Head and Neck Neoplasms (1)  ·  Hematologic Neoplasms (1)  ·  Lymphoma (1)  ·  Lymphoma, Non-Hodgkin (1)  ·  Neoplasms (1)  ·  Squamous Cell Carcinoma of Head and Neck (1)

Sponsors

Takeda (5)  ·  Presage Biosciences (1)

Countries

United States (5)  ·  Canada (2)  ·  China (2)  ·  Japan (2)  ·  Brazil (1)  ·  Croatia (1)  ·  France (1)  ·  Germany (1)  ·  Hungary (1)  ·  Italy (1)  ·  Latvia (1)  ·  Lithuania (1)  ·  Poland (1)  ·  Spain (1)  ·  Switzerland (1)

Results publications

PMID 35226739, PMID 40373381

NIH funding

2023 (1)