6 completed, 1 active not recruiting, 1 unknown. 4 Phase 3, 2 Phase 4, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 4 | Completed 4 |
| Phase 4 | 2 | Completed 1, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Active not recruiting 1 |
Follow spinosad: new trials by email Literature Review of spinosad trials Research Report on spinosad
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 2, Controlled, Double Blind, Randomized and Multicenter Study to Compare Efficacy and Safety of a Novel Topical Therapy (APT-001, Spinosad 1.8%) in Patients With Blepharitis. APT-001 topical ophthalmic ointment (spinosad), Vehicle control for APT-001 topical ophthalmic ointment - Blepharitis | Phase 2 | Active not recruiting | Aperta Biosciences, LLC | 100 | 2025-11-01 | 2026-05-19 |
| PK and Safety Study of Natroba Topical Suspension 0.9% in Subjects 1 Month to 3 Years 11 Months of Age With Scabies Spinosad Topical - Scabies | Phase 4 | Unknown | Cipher Pharmaceuticals Inc. | 50 | 2022-03-04 | 2025-02-14 |
| Phase 3 Trial to Assess the Safety and Efficacy of Natroba for the Treatment of Scabies spinosad topical suspension, 0.9%, Placebo - Scabies | Phase 3 | Completed | ParaPRO LLC | 280 | 2017-05-10 | 2021-05-21 |
| Phase 3 Trial to Assess the Safety and Efficacy of Natroba for the Treatment of Scabies spinosad topical suspension, 0.9%, Placebo - Scabies | Phase 3 | Completed | ParaPRO LLC | 291 | 2017-05-02 | 2021-05-19 |
| Pharmacokinetic (PK) and Tolerance Study of Natroba Topical Suspension in Pediatrics With an Active Head Lice Infestation spinosad - Pediculosis | Phase 4 | Completed | ParaPRO LLC | 26 | 2011-09-01 | 2012-11-22 |
| Phototoxicity Potential of NatrOVA Creme Rinse - 1% Spinosad (the active ingredient in NatrOVA), placebo - Head Lice | Phase 1 | Completed | ParaPRO LLC | 37 | 2007-12-01 | 2008-05-20 |
| Safety and Efficacy Study of NatrOVA Creme Rinse - 1% and NIX Creme Rinse in Subjects 6 Months or Older With Head Lice Spinosad, Permethrin 1% - Pediculosis | Phase 3 | Completed | ParaPRO LLC | 558 | 2007-09-01 | 2012-10-11 |
| Safety and Efficacy Study of NatrOVA Creme Rinse - 1% and NIX Creme Rinse in Subjects 6 Months or Older With Head Lice Spinosad, Permethrin 1% - Pediculus Capitis Infestation | Phase 3 | Completed | ParaPRO LLC | 480 | 2007-09-01 | 2012-10-11 |
Scabies (3) · Lice Infestations (2) · Blepharitis (1)
ParaPRO LLC (6) · Aperta Biosciences, LLC (1) · Cipher Pharmaceuticals Inc. (1)
United States (7) · Guatemala (1)
Bill Miller, MD (2) · Kerry W Mettert, MBA (2) · Dowling B Stough, M.D. (1) · Jeffrey C Seiler, M.D. (1) · John V Murray, MD (1) · Josue Moran, Ph.D. (1) · Julie Aker, MT(ASCP) (1) · Sharda Angl (1) · William Miller, MD (1)