6 completed, 1 active not recruiting, 1 recruiting, 1 terminated. 9 Phase 3.
By phase and status
Follow selexipag: new trials by email Literature Review of selexipag trials Research Report on selexipag
Trials (filtered) newest first · largest first
All 9 trials
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other Option Macitentan, Selexipag, Macitentan/Tadalafil FDC - Hypertension, Pulmonary | Phase 3 | Recruiting | 280 | 2022-05-04 | 2026-11-03 |
A Study of Selexipag in Participants Who Participated in a Previous Selexipag Study Selexipag - Hypertension, Pulmonary | Phase 3 | Completed | 43 | 2021-05-03 | 2025-05-01 |
A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial Hypertension Selexipag, Placebo, Standard of Care (SOC): Endothelin receptor antagonist - Hypertension, Pulmonary | Phase 3 | Active not recruiting | 138 | 2020-01-16 | 2026-11-03 |
A Study to Find Out if Selexipag is Effective and Safe in Patients With Chronic Thromboembolic Pulmonary Hypertension When the Disease is Inoperable or Persistent/Recurrent After Surgery and/or Interventional Treatment Selexipag, Placebo - Chronic Thromboembolic Pulmonary Hypertension | Phase 3 | Terminated | 128 | 2019-01-23 | 2024-06-21 |
Safety Study of the Switch From Oral Selexipag to Intravenous Selexipag in Subjects With Stable Pulmonary Arterial Hypertension i.v. selexipag, oral selexipag (Uptravi) - Pulmonary Arterial Hypertension | Phase 3 | Completed | 20 | 2017-12-04 | 2025-06-29 |
The Efficacy and Safety of Initial Triple Versus Initial Dual Oral Combination Therapy in Patients With Newly Diagnosed Pulmonary Arterial Hypertension Macitentan, Tadalafil, Selexipag - Pulmonary Arterial Hypertension | Phase 3 | Completed | 247 | 2016-05-01 | 2025-03-30 |
Study to Assess the Tolerability and the Safety of the Transition From Inhaled Treprostinil to Oral Selexipag in Patients With Pulmonary Arterial Hypertension Selexipag - Pulmonary Arterial Hypertension | Phase 3 | Completed | 34 | 2015-10-12 | 2018-01-23 |
ACT-293987 in Pulmonary Arterial Hypertension ACT-293987 - Pulmonary Arterial Hypertension | Phase 3 | Completed | 709 | 2010-07-07 | 2025-03-30 |
Selexipag (ACT-293987) in Pulmonary Arterial Hypertension Selexipag, Placebo - Pulmonary Arterial Hypertension | Phase 3 | Completed | 1156 | 2009-12-01 | 2025-10-27 |
Conditions studied
Pulmonary Arterial Hypertension (6) · Hypertension, Pulmonary (3)
Sponsors
Actelion (9)
Countries
United States (7) · Belgium (6) · Germany (6) · South Korea (6) · Taiwan (6) · Ukraine (6) · Australia (5) · Belarus (5) · Canada (5) · China (5) · Hungary (5) · Poland (5) · Russia (5) · Spain (5) · Sweden (5)
Top investigators
Aline Frey (2) · Julian Borissoff, MD, PhD (1) · Ralph Preiss (1)
Results publications
PMID 34727317, PMID 24392948, PMID 26699168, PMID 28556581, PMID 28818881, PMID 29307087, PMID 29447737, PMID 30391194, PMID 30982349, PMID 33536021, PMID 33545163, PMID 34593120, PMID 39222737, PMID 39326918
NIH funding
2009 (1), 2016 (1), 2018 (1), 2019 (1), 2023 (1)