sebetralstat: Clinical Trials

4 trials of sebetralstat, newest first

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4 completed. 4 Phase 3.

By phase and status

PhaseTrialsStatus
Phase 34Completed 4

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Trials (filtered) newest first · largest first

All 4 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Open-Label Safety, PK, and Efficacy Trial of Sebetralstat (KVD900) in Pediatric Patients (Ages 2-11) With HAE Type I or II
KVD900 150 mg, KVD900 300 mg, KVD900 600 mg - Hereditary Angioedema
Phase 3CompletedKalVista Pharmaceuticals, Ltd.362024-08-012026-08-05
An Open-label Extension Trial to Evaluate the Long-term Safety of KVD900 (Sebetralstat) for On-Demand Treatment of Angioedema Attacks in Adolescent and Adult Patients With Hereditary Angioedema (HAE)
KVD900 600 mg, KVD900 300 mg - Hereditary Angioedema
Phase 3CompletedKalVista Pharmaceuticals, Ltd.1452022-10-242026-06-05
PK Subtrial in Adolescent Patients With HAE Type I or II Participating in the KVD900-302 Trial
KVD900 600 mg, Drug: KVD900 300 mg - Hereditary Angioedema
Phase 3CompletedKalVista Pharmaceuticals, Ltd.112022-10-242026-06-08
A Phase III, Crossover Trial Evaluating the Efficacy and Safety of KVD900 (Sebetralstat) for On-Demand Treatment of Angioedema Attacks in Adolescent and Adult Patients With Hereditary Angioedema (HAE)
Placebo, KVD900 600 mg, KVD900 300 mg - Hereditary Angioedema
Phase 3CompletedKalVista Pharmaceuticals, Ltd.1362022-02-222025-05-02

Conditions studied

Angioedemas, Hereditary (4)

Sponsors

KalVista Pharmaceuticals, Ltd. (4)

Countries

Canada (4)  ·  France (4)  ·  Germany (4)  ·  Israel (4)  ·  Japan (4)  ·  United States (4)  ·  Australia (3)  ·  Bulgaria (3)  ·  Greece (3)  ·  Italy (3)  ·  Netherlands (3)  ·  New Zealand (3)  ·  Romania (3)  ·  Slovakia (3)  ·  Spain (3)

Results publications

PMID 40886933, PMID 36774155, PMID 41252457, PMID 42318595, PMID 42436759