4 completed, 1 no longer available, 1 terminated. 2 Phase 1, 2 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Completed 1, Terminated 1 |
| Phase 2 | 2 | Completed 2 |
| Phase 3 | 1 | Completed 1 |
Follow rindopepimut: new trials by email Literature Review of rindopepimut trials Research Report on rindopepimut
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Rindopepimut/GM-CSF in Patients With Relapsed EGFRvIII-Positive Glioblastoma Bevacizumab, Rindopepimut (CDX-110) with GM-CSF, KLH - Glioblastoma, Small Cell Glioblastoma | Phase 2 | Completed | Celldex Therapeutics | 127 | 2011-12-01 | 2020-02-17 |
| Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma Rindopepimut (CDX-110) with GM-CSF, Temozolomide, KLH - Glioblastoma, Small Cell Glioblastoma | Phase 3 | Completed | Celldex Therapeutics | 745 | 2011-11-01 | 2018-01-16 |
| Phase I Rindopepimut After Conventional Radiation in Children w/ Diffuse Intrinsic Pontine Gliomas Rindopepimut - Brain Cancer, Brain Stem Tumors | Phase 1 | Terminated | Paul Graham Fisher | 3 | 2011-06-01 | 2021-09-27 |
| Phase II Study of Rindopepimut (CDX-110) in Patients With Glioblastoma Multiforme CDX-110 with GM-CSF, Temozolomide - Malignant Glioma | Phase 2 | Completed | Celldex Therapeutics | 82 | 2007-08-01 | 2018-01-16 |
| Chemotherapy, Radiation Therapy, and Vaccine Therapy With Basiliximab in Treating Patients With Glioblastoma Multiforme That Has Been Removed by Surgery PEP-3-KLH conjugate vaccine, daclizumab, temozolomide - Malignant Neoplasms of Brain | Phase 1 | Completed | John Sampson | 16 | 2007-03-01 | 2016-01-21 |
| Expanded Access (Compassionate Use) Treatment Protocol Rindopepimut rindopepimut - Recurrent GBM | No longer available | Celldex Therapeutics | 2017-10-18 |
Glioblastoma (4) · Brain Neoplasms (3) · Gliosarcoma (3) · Glioma (2) · Neoplasms (2) · Brain Stem Neoplasms (1) · Recurrence (1)
Celldex Therapeutics (4) · John Sampson (1) · Paul Graham Fisher (1)
United States (5) · Australia (1) · Austria (1) · Belgium (1) · Brazil (1) · Canada (1) · Colombia (1) · Czechia (1) · France (1) · Germany (1) · Greece (1) · Hungary (1) · India (1) · Israel (1) · Italy (1)
Duane Mitchell, MD, PhD (1) · Paul Graham Fisher (1)
PMID 22383993, PMID 25586468, PMID 26670466, PMID 28844499, PMID 32034072, PMID 36346112
1RC2CA148491-01 (1), R21CA132891 (1)