9 completed, 1 active not recruiting. 10 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Completed 9, Active not recruiting 1 |
Follow Restylane Defyne: new trials by email Literature Review of Restylane Defyne trials Research Report on Restylane Defyne
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Restylane Treatment Algorithm Approach for Participants With Appearance of Insufficient Bone Structure in the Lower Face Alone or in Combination With Facial Soft Tissue Deficiencies Restylane Shaype, Restylane Defyne, Restylane Lyft lidocaine - Chin Augmentation | Not applicable | Completed | Galderma R&D | 45 | 2024-05-13 | 2025-01-31 |
| Safety and Efficacy of Fillers for Contouring the Jawline Restylane Defyne, Restylane Lyft - Jawline Contour Deficit | Not applicable | Completed | Erevna Innovations Inc. | 40 | 2021-11-11 | 2024-05-23 |
| LifeSprout Lumina™ Study in the Treatment of Nasolabial Folds Study Product, Active Control - Nasolabial Fold | Not applicable | Active not recruiting | LifeSprout, Inc. | 118 | 2021-03-02 | 2022-09-10 |
| Restylane Defyne in a Stepwise Treatment Approach Restylane Defyne - Lower Face Folds and Lines | Not applicable | Completed | Galderma R&D | 62 | 2020-12-07 | 2023-04-14 |
| A Study to Evaluate the Safety and Effectiveness Assessments of Restylane-Defyne for Punctual Occlusion Restylane Defyne - Dry Eye | Not applicable | Completed | John C Meyer, MD | 17 | 2019-07-18 | 2019-09-06 |
| A Study to Evaluate Effectiveness and Safety of Hyaluronic Acid (HA) Fillers Restylane Volyme, Restylane Defyne, Restylane Lyft Lidocaine - Volume Deficiency of the Midface | Not applicable | Completed | Galderma R&D | 90 | 2018-11-09 | 2022-08-26 |
| A Study to Evaluate the Safety and Effectiveness of Restylane-Defyne for Punctual Occlusion Restylane Defyne - Mild to Moderate Dry Eye Disease | Not applicable | Completed | John C Meyer, MD | 14 | 2018-10-17 | 2018-12-10 |
| Restylane Defyne for Correction of Chin Retrusion Restylane Defyne - Chin Retrusion | Not applicable | Completed | Galderma R&D | 148 | 2018-10-08 | 2024-06-12 |
| A Study to Evaluate the Safety and Efficacy of Restylane Defyne for Chin Augmentation and Correction of Chin Retrusion Restylane Defyne - Chin Retrusion, Chin Augmentation | Not applicable | Completed | Galderma R&D | 140 | 2018-08-21 | 2022-10-06 |
| Restylane Defyne Compared to Restylane for Correction of Moderate to Severe Nasolabial Folds Restylane Defyne, Restylane - Nasolabial Folds in Chinese Population | Not applicable | Completed | Galderma R&D | 175 | 2017-01-16 | 2023-11-03 |
Galderma R&D (6) · John C Meyer, MD (2) · Erevna Innovations Inc. (1) · LifeSprout, Inc. (1)
United States (4) · Canada (2) · China (2) · Italy (2) · United Kingdom (2) · Belgium (1) · Brazil (1) · Germany (1) · Portugal (1)
John C Meyer, MD (2) · Q-Med AB (2) · Andreas Nikolis, MD (1) · Sashank Reddy, M.D. (1)