9 completed, 1 unknown. 4 Phase 3, 3 Phase 1, 2 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 4 | Completed 3, Unknown 1 |
| Phase 1 | 3 | Completed 3 |
| Phase 2 | 2 | Completed 2 |
| Phase 4 | 1 | Completed 1 |
Follow RBP-6000: new trials by email Literature Review of RBP-6000 trials Research Report on RBP-6000
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Buprenorphine Extended-Release Subcutaneous Injection (RBP-6000) in High-risk Users Transmucosal Buprenorphine, Extended-release Buprenorphine - Moderate to Severe Opioid-use Disorder | Phase 4 | Completed | Indivior Inc. | 785 | 2021-10-26 | 2026-02-06 |
| Community Studies of Long Acting Buprenorphine (CoLAB) RBP-6000 - Opioid Dependence | Phase 3 | Unknown | The University of New South Wales | 100 | 2019-05-22 | 2020-03-05 |
| Open-Label Treatment Extension Study RBP-6000 - Opioid Use Disorder, Opioid-related Disorders | Phase 3 | Completed | Indivior Inc. | 208 | 2016-08-17 | 2018-11-29 |
| Pharmacokinetics, Safety, and Tolerability of Depot Buprenorphine at Three Different Molecular Weights in Treatment-Seeking Subjects With Opioid Use Disorder RBP-6000, SUBOXONE Sublingual Film - Opioid Use Disorder | Phase 1 | Completed | Indivior Inc. | 47 | 2015-09-01 | 2017-01-31 |
| Safety and Tolerability Study of Depot Buprenorphine in Treatment Seeking Subjects With Opioid Use Disorder SUBOXONE sublingual film, RBP-6000 - Opioid Use Disorder, Opioid-related Disorders | Phase 3 | Completed | Indivior Inc. | 775 | 2015-07-27 | 2018-03-29 |
| Treatment Seeking Participants With Opioid Use Disorders Assessing Tolerability of Depot Injections of Buprenorphine SUBOXONE, RBP-6000, Placebo - Opioid Dependence, Opioid Related Disorders | Phase 3 | Completed | Indivior Inc. | 665 | 2015-01-28 | 2018-02-20 |
| Multiple Dose Study of Blockade of Opioid Effects by Injections of Buprenorphine in Participants With Opioid Disorder Buprenorphine, buprenorphine and naloxone, hydromorphone - Opioid Use Disorder | Phase 2 | Completed | Indivior Inc. | 39 | 2013-11-01 | 2018-04-24 |
| Multiple Dose Pharmacokinetics Depot Buprenorphine in Opioid-Dependent Subjects RBP-6000, Subutex - Opioid Related Disorder | Phase 2 | Completed | Indivior Inc. | 124 | 2012-10-01 | 2018-02-23 |
| Single Ascending Dose Study of RBP-6000 RBP-6000, Suboxone - Opioid Use Disorder | Phase 1 | Completed | Indivior Inc. | 48 | 2012-07-01 | 2016-12-26 |
| Single-dose, Study of RBP-6000 in Opioid Dependent Individuals RBP-6000 - Opioid Use Disorder | Phase 1 | Completed | Indivior Inc. | 18 | 2010-11-01 | 2016-05-09 |
Indivior Inc. (9) · The University of New South Wales (1)
United States (9) · Australia (1) · Canada (1)
Bradley D Vince, DO (1) · Michael Farrell (1)
PMID 35287034, PMID 37657559, PMID 36467036, PMID 26650971, PMID 30792007, PMID 32737087, PMID 32920647, PMID 34736130, PMID 34794061, PMID 38042801, PMID 38382354, PMID 39957328, PMID 41085986, PMID 41240750, PMID 41405885