4 unknown, 2 completed, 1 terminated, 1 withdrawn. 5 Phase 3, 3 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Unknown 3, Completed 1, Terminated 1 |
| Phase 2 | 3 | Completed 1, Terminated 1, Unknown 1 |
| Phase 1 | 2 | Completed 1, Withdrawn 1 |
Follow polysaccharide-K: new trials by email Literature Review of polysaccharide-K trials Research Report on polysaccharide-K
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vaccine Therapy With or Without Polysaccharide-K in Patients With Stage IV HER2 Positive Breast Cancer Receiving HER2-Targeted Monoclonal Antibody Therapy HER-2/neu Intracellular Domain Protein, Laboratory Biomarker Analysis, Pertuzumab - HER2/Neu Positive, Recurrent Breast Carcinoma | Phase 1 / Phase 2 | Completed | University of Washington | 31 | 2014-02-05 | 2023-04-18 |
| A Phase 1b Dose Escalation Trial of PSK®/Placebo With Docetaxel to Treat Metastatic Castration-resistant Prostate Cancer Docetaxel, PSK®, Docetaxel, Placebo - Prostatic Neoplasms | Phase 1 | Withdrawn | Bastyr University | 2013-05-01 | 2015-10-27 | |
| Study of TS-1 or TS-1 + PSK for Gastric Cancer Patients Tegafur-gimeracil-oteracil potassium (TS-1), Krestin (PSK) - Gastric Cancer | Phase 3 | Unknown | Tokyo Metropolitan Oncology Group | 480 | 2008-06-01 | 2012-03-22 |
| Feasibility Study of CDDP + CPT-11 + PSK for Extensive-Stage Disease (ED) Small Cell Lung Cancer Irinotecan hydrochloride, Cisplatin, Krestin - Small Cell Lung Cancer | Phase 2 | Unknown | University of Toyama | 45 | 2007-11-01 | 2008-09-03 |
| Phase II Study of TS-1 Therapy and TS-1+PSK Therapy Against Advanced Gastric Carcinoma Tegafur/gimeracil/oteracil potassium (S-1), Krestin (PSK), Tegafur/gimeracil/oteracil potassium (S-1) - Gastric Cancer | Phase 2 / Phase 3 | Terminated | Eastern Network of Cancer Immunological Therapy, Japan | 13 | 2006-10-01 | 2009-01-23 |
| A Phase III Trial Comparing UFT+PSK to UFT+LV in Stage IIB, III Colorectal Cancer Tegafur-uracil (UFT), Calcium folinate (LV), Krestin (PSK) - Colorectal Cancer | Phase 3 | Unknown | Multicenter Clinical Study Group of Osaka, Colorectal Cancer Treatment Group | 380 | 2006-03-01 | 2012-10-26 |
| Randomized Phase III Adjuvant Study for Stage III Colorectal Cancer UFT, USEL/Leucovorin, Krestin - Colorectal Cancer | Phase 3 | Unknown | Hokkaido Gastrointestinal Cancer Study Group | 340 | 2005-04-01 | 2010-05-26 |
| Randomized Controlled Study of Postoperative Adjuvant Therapy for Gastric Cancer Using TS-1 or TS-1+PSK Tegafur-gimeracil-oteracil potassium (TS-1), Krestin (PSK) - Gastric Cancer | Phase 3 | Completed | Hokuriku-Kinki Immunochemotherapy Study Group | 255 | 2005-03-01 | 2016-06-07 |
Stomach Neoplasms (3) · Colorectal Neoplasms (2) · Adenocarcinoma (1) · Breast Neoplasms (1) · Neoplasm Metastasis (1) · Neoplasms (1) · Prostatic Neoplasms (1) · Small Cell Lung Carcinoma (1)
Bastyr University (1) · Eastern Network of Cancer Immunological Therapy, Japan (1) · Hokkaido Gastrointestinal Cancer Study Group (1) · Hokuriku-Kinki Immunochemotherapy Study Group (1) · Multicenter Clinical Study Group of Osaka, Colorectal Cancer Treatment Group (1) · Tokyo Metropolitan Oncology Group (1) · University of Toyama (1) · University of Washington (1)
Japan (6) · United States (2)
Celestia Higano, MD (1) · Cynthia A Wenner, Ph.D (1) · Hideaki Tahara, MD (1) · Koichi Miwa, MD, PhD (1) · Leanna J Standish, PhD, ND, LAc (1) · Lupe Salazar (1) · Masahiro Asaka, MD, PhD (1) · Masatsugu Kitamura, MD (1) · Morito Monden, MD, PhD (1) · Tatsuhiko Kashii, MD, PhD (1)
P30CA015704 (1), U19AT006028 (1)