4 completed, 1 recruiting, 1 terminated. 5 Phase 1, 4 Phase 2, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 4, Terminated 1 |
| Phase 2 | 4 | Completed 3, Terminated 1 |
| Early Phase 1 | 1 | Recruiting 1 |
Follow PolyICLC: new trials by email Literature Review of PolyICLC trials Research Report on PolyICLC
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| FUSA With Intratumoral PolyICLC in Regionally Advanced Resectable Melanoma Echopulse or Echopulse HD, PolyICLC - Advanced Melanoma | Early Phase 1 | Recruiting | University of Virginia | 11 | 2024-09-27 | 2025-11-20 |
| Melanoma Vaccine Against Neoantigen and Shared Antigens by CD40 Activation and TLR Agonists In Patients With Melanoma (Including Ocular Melanoma) 6MHP, NeoAg-mBRAF, PolyICLC - Melanoma, Ocular Melanoma | Phase 1 / Phase 2 | Completed | Craig L Slingluff, Jr | 22 | 2020-09-28 | 2024-07-16 |
| Vaccination With 6MHP, With or Without Systemic CDX-1127, in Patients With Stage II-IV Melanoma 6MHP, Montanide ISA-51, polyICLC - Melanoma | Phase 1 / Phase 2 | Completed | Craig L Slingluff, Jr | 33 | 2018-11-13 | 2024-02-06 |
| Safety Study of a Helper Peptide Vaccine Plus Adjuvant Combinations for the Treatment of Melanoma 6MHP, Montanide ISA-51, polyICLC - Melanoma | Phase 1 / Phase 2 | Terminated | Craig L Slingluff, Jr | 48 | 2015-05-12 | 2023-10-30 |
| Phase I/II Trial of a Long Peptide Vaccine (LPV7) Plus TLR Agonists Peptide Vaccine (LPV7) + Tetanus peptide, PolyICLC, Resiquimod - Melanoma, Metastatic Melanoma | Phase 1 / Phase 2 | Completed | Craig L Slingluff, Jr | 50 | 2014-05-01 | 2024-02-28 |
| Evaluation of a Multi-phosphopeptide Vaccine Plus PolyICLC in Participants With High Risk and Advanced Malignancies pBCAR3-phosphopeptide, pIRS2-phosphopeptide, 2-MpP (pBCAR3-phosphopeptide + pIRS2-phosphopeptide) - Melanoma | Phase 1 | Completed | Craig L Slingluff, Jr | 15 | 2013-05-01 | 2016-08-12 |
Melanoma (6) · Neoplasms (1) · Nevus (1) · Uveal Melanoma (1)
Craig L Slingluff, Jr (5) · University of Virginia (1)
United States (6)
Craig L. Slingluff, Jr., MD (3) · Craig L Slingluff, Jr., M.D. (1) · Craig L Slingluff, Jr., MD (1) · Lynn T Dengel, MD (1) · Victor Engelhard, PhD (1)