1 completed, 1 terminated. 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 2 | Completed 1, Terminated 1 |
Follow Placebo to match metoprolol succinate: new trials by email Literature Review of Placebo to match metoprolol succinate trials Research Report on Placebo to match metoprolol succinate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol Succinate in Adults With Symptomatic oHCM Aficamten (CK-3773274) (5 mg, 10 mg, 15 mg and 20 mg), Placebo to match aficamten, Metoprolol succinate (50 mg, 100 mg, 150 mg and 200 mg) - Obstructive Hypertrophic Cardiomyopathy (oHCM) | Phase 3 | Completed | Cytokinetics | 175 | 2023-06-20 | 2026-06-09 |
| Enoximone Plus Extended-Release Metoprolol Succinate in Subjects With Advanced Chronic Heart Failure Enoximone, Metoprolol succinate, Placebo to match enoximone - Heart Failure, Congestive | Phase 3 | Terminated | Gilead Sciences | 175 | 2003-07-01 | 2014-01-10 |
Cardiomyopathy, Hypertrophic (1) · Heart Failure (1)
Cytokinetics (1) · Gilead Sciences (1)
United States (2) · Brazil (1) · Canada (1) · China (1) · Denmark (1) · France (1) · Germany (1) · Hungary (1) · Israel (1) · Italy (1) · Netherlands (1) · Spain (1) · United Kingdom (1)
PMID 39909646, PMID 40888697, PMID 40932433, PMID 41348072, PMID 41493295, PMID 42307914, PMID 42624353, PMID 42667283
2023 (1)