8 completed, 2 withdrawn, 1 unknown. 3 Phase 4, 2 Phase 2, 1 Early Phase 1, 1 Not applicable, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 3 | Completed 2, Unknown 1 |
| Phase 2 | 2 | Completed 1, Withdrawn 1 |
| Early Phase 1 | 1 | Withdrawn 1 |
| Not applicable | 1 | Completed 1 |
| Phase 1 | 1 | Withdrawn 1 |
| Phase 3 | 1 | Completed 1 |
Follow Picato: new trials by email Literature Review of Picato trials Research Report on Picato
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Ingenol Mebutate for Actinic Cheilitis Treatment Ingenol mebutate gel - Actinic Cheilitis | Phase 1 / Phase 2 | Withdrawn | Instituto Nacional de Cancer, Brazil | 2020-02-01 | 2019-06-19 | |
| Picato for the Treatment of Molluscum Contagiosum in Immunocompromised Patients Picato - Molluscum Contagiosum | Early Phase 1 | Withdrawn | Center for Clinical Studies, Texas | 2017-12-20 | 2022-04-01 | |
| Efficacy of Ingenol Mebutate on Actinic Keratoses and Field Cancerization vs Cryotherapy Ingenol mebutate, cryotherapy - Actinic Keratosis | Phase 4 | Completed | University of Campania Luigi Vanvitelli | 50 | 2017-04-12 | 2019-09-24 |
| Safety and Efficacy of Ingenol Mebutate Gel 0.015% for Treatment of AK on the Face in Solid Organ Transplant Recipients ingenol mebutate gel 0.015% - Actinic Keratosis | Phase 4 | Completed | University of California, San Francisco | 20 | 2016-10-06 | 2022-03-09 |
| The Use of Picato® (Ingenol Mebutate) to Treat Actinic Keratosis in Standard Clinical Practice Ingenol mebutate - Actinic Keratosis | Completed | LEO Pharma | 440 | 2015-12-01 | 2019-01-22 | |
| Safety and Efficacy of Repeat Use of Picato® 0.05% in the Treatment of Anogenital Warts Picato - Anogenital Warts | Phase 2 | Completed | LEO Pharma | 40 | 2015-02-01 | 2025-02-24 |
| A Study of Equivalence of Generic Ingenol Mebutate Gel 0.05% and Picato Gel 0.05% in Subjects With Actinic Keratosis Ingenol Mebutate (Picato®), Generic Ingenol Mebutate, Vehicle Foam - Actinic Keratosis | Phase 3 | Completed | Actavis Inc. | 441 | 2015-02-01 | 2020-05-12 |
| IM Versus 5-FU Versus IMI Versus MAL-PDT in Treatment of Actinic Keratosis Imiquimod, 5-fluorouracil, Ingenol mebutate - Keratosis, Actinic | Phase 4 | Unknown | Maastricht University Medical Center | 624 | 2014-11-01 | 2017-10-30 |
| The Real Life Topical Field Treatment of Actinic Keratosis Study Ingenol mebutate, 5-fluorouracil, Imiquimod - Actinic Keratosis | Completed | LEO Pharma | 1168 | 2014-07-01 | 2019-12-13 | |
| Safety and Tolerability Study of Ingenol Mebutate Compared to 5-FU to Treat Facial Actinic Keratosis ingenol mebutate, 5% 5-FU - Actinic Keratosis | Not applicable | Completed | University of Sao Paulo | 100 | 2014-05-01 | 2014-09-17 |
| TreatMent of ActInic KerAtosis Lesions : pharmacoepiDemiological Study of the Impact in Real Life of ingenOl Mebutate Gel (Picato®) on Patients Satisfaction Ingenol mebutate - Actinic Keratosis | Completed | LEO Pharma | 1218 | 2014-04-01 | 2023-06-09 |
Keratosis, Actinic (8) · Actinic cheilitis (1) · Condylomata Acuminata (1) · Molluscum Contagiosum (1)
LEO Pharma (4) · Actavis Inc. (1) · Center for Clinical Studies, Texas (1) · Instituto Nacional de Cancer, Brazil (1) · Maastricht University Medical Center (1) · University of California, San Francisco (1) · University of Campania Luigi Vanvitelli (1) · University of Sao Paulo (1)
United States (3) · Netherlands (2) · Brazil (1) · Denmark (1) · Greece (1) · Italy (1)
Daniel Cohen Goldemberg, PhD (1) · Giuseppe Argenziano, Prof (1) · Klara Mosterd, MD, PhD (1) · Kostas Sitaras, MD (1) · Luis Antonio Torezan, PhD (1) · Oleg Khatsenko, Ph.D (1) · Sarah Arron, MD, PhD (1) · Sarah Moumane, MD (1) · Stephen K Tyring, MD, PhD (1)
PMID 11966728, PMID 12533168, PMID 15168956, PMID 18067627, PMID 20231500, PMID 20725550, PMID 24672213, PMID 25727104, PMID 30855743, PMID 31961446, PMID 33476658, PMID 35475852, PMID 7947197
2014 (1)