9 completed, 2 unknown. 3 Not applicable, 3 Phase 4, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 3 |
| Phase 4 | 3 | Unknown 2, Completed 1 |
| Phase 3 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
Follow pergoveris: new trials by email Literature Review of pergoveris trials Research Report on pergoveris
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| An Ethno-bridging Study of Pergoveris in Healthy Premenopausal Participants of Japanese or Caucasian Origin Desogestrel and ethinylestradiol fixed dose combination, Follitropin alfa/lutropin alfa - Fertility | Phase 1 | Completed | Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany | 24 | 2025-11-24 | 2026-03-18 |
| Double Ovarian Stimulation as Accumulation Strategy for Older Infertile Patients With Suboptimal Ovarian Response Pergoveris, Clomiphene - Infertility, Female, Ovarian Stimulation | Phase 4 | Unknown | Nova Clinic, Russia | 120 | 2017-12-01 | 2018-01-17 |
| Corifollitropin Alfa Combined With Menotropin Versus Follitropin and Lutropin Alfa in Expected Suboptimal Responders Corifollitropin alfa and menotropin, Follitropin alfa and lutropin alfa - Infertility, Female | Phase 4 | Completed | D.O. Ott Research Institute of Obstetrics, Gynecology, and Reproductology | 32 | 2017-09-04 | 2019-09-12 |
| Androgenic Profile Following Controlled Ovarian Stimulation recombinant gonadotropins, HP-HMG - Infertility, Female | Phase 4 | Unknown | Sheba Medical Center | 100 | 2016-12-01 | 2016-12-20 |
| Phase 3 Study to Evaluate the Efficacy and Safety of Pergoveris® in Assisted Reproductive Technology (ESPART) Pergoveris®, GONAL-f®, Recombinant human chorionic gonadotrophin (r-hCG) - Infertility | Phase 3 | Completed | Merck KGaA, Darmstadt, Germany | 939 | 2014-01-31 | 2017-08-24 |
| Efficacy of Pergoveris in Aged IVF Patients Pergoveris (FSH and LH), Follitropin alpha (FSH) - Infertility | Not applicable | Completed | Vietnam National University | 240 | 2012-10-01 | 2014-12-25 |
| Comparing Ovarian Stimulation for Assisted Reproduction With Two Different Forms of Pituitary Suppression Pergoveris in long protocol with GnRH agonist, Pergoveris in GnRH antagonist protocol - Female Infertility Due to Nonimplantation of Ovum, Complications Associated With Artificial Fertilization | Not applicable | Completed | University Hospital, Basel, Switzerland | 5 | 2012-04-01 | 2017-05-01 |
| A Korean Post-Marketing Surveillance Study On Pergoveris® (Follitropin Alfa + Lutropin Alfa) Pergoveris® - Infertility | Completed | Merck KGaA, Darmstadt, Germany | 600 | 2011-08-14 | 2019-07-19 | |
| PERgoveriS In Stratified Treatment for Assisted Reproductive Technique Gonal-f®, Pergoveris®, Recombinant human chorionic gonadotropin (r-hCG) - Assisted Reproductive Techniques, Reproductive Technology, Assisted | Phase 3 | Completed | Merck KGaA, Darmstadt, Germany | 202 | 2011-05-31 | 2021-05-28 |
| Clinical Outcomes in WHO Type I Anovulatory Women Using r-hFSH+r-hLH in a 2:1 Ratio or hMG-HP Pergoveris: 150IU r-hFSH + 75IU r-hLH, Menopur: HMG-HP (150 IU) - Hypogonadotropic Hypogonadism | Not applicable | Completed | Centro Riproduzione e Andrologia | 40 | 2011-03-01 | 2012-06-20 |
| Ovarian Stimulation With Recombinant Gonadotropins vs. Human Menopausal Gonadotropin in In Vitro Fertilization rFSH plus rLH, hMG - Infertility | Completed | University of Turin, Italy | 848 | 2010-03-01 | 2014-12-23 |
Infertility (5) · Infertility, Female (3) · Helping Behavior (2) · Hypogonadism (1)
Merck KGaA, Darmstadt, Germany (3) · Centro Riproduzione e Andrologia (1) · D.O. Ott Research Institute of Obstetrics, Gynecology, and Reproductology (1) · Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany (1) · Nova Clinic, Russia (1) · Sheba Medical Center (1) · University Hospital, Basel, Switzerland (1) · University of Turin, Italy (1) · Vietnam National University (1)
Italy (3) · Russia (3) · Germany (2) · United Kingdom (2) · Denmark (1) · Finland (1) · France (1) · Greece (1) · Netherlands (1) · Poland (1) · Slovakia (1) · South Korea (1) · Switzerland (1) · Vietnam (1)
Alberto Revelli, MD PhD (1) · Alexdandr Gzgzyan, Prof, PhD (1) · Christian De Geter, Prof. (1) · Konstantin Dancheev (1) · Salvatore Longobardi, MD (1) · Tuong M Ho, MD (1)
PMID 23095369, PMID 25740882, PMID 26141305, PMID 26194884, PMID 28137754, PMID 34937512