6 completed, 3 terminated, 1 withdrawn. 6 Phase 3, 2 Not applicable, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Completed 4, Terminated 2 |
| Not applicable | 2 | Completed 1, Withdrawn 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 4 | 1 | Terminated 1 |
Follow optivate: new trials by email Literature Review of optivate trials Research Report on optivate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Post-Marketing Safety Study Following Long-Term Prophylactic OptivateTreatment in Subjects With Severe Haemophilia A Optivate 500IU - Haemophilia A | Phase 4 | Terminated | Bio Products Laboratory | 7 | 2014-11-21 | 2021-07-22 |
| Rescue Immunotolerance Study in Induction of Immune Tolerance (ITI)-Experienced Patients (RES.I.S.T. Experienced) VWF/FVIII concentrates - Severe Hemophilia A | Not applicable | Completed | City of Hope Medical Center | 3 | 2009-11-03 | 2021-08-23 |
| Study of First TIME Immunotolerance Induction in Severe Hemophilia A Patients With Inhibitor at High Risk of Failure: Comparison With FVIII Concentrates With or Without Von Willebrand Factor - RES.I.S.T. Naive FVIII Concentrates, FVIII/VWF concentrates - Severe Hemophilia A | Not applicable | Withdrawn | City of Hope Medical Center | 2009-09-25 | 2020-12-17 | |
| Optivate in People With Von Willebrand Disease Undergoing Surgery Optivate - Von Willebrand Disease | Phase 3 | Terminated | Bio Products Laboratory | 25 | 2007-02-01 | 2010-03-03 |
| A Study With OPTIVATE® in People With Von Willebrand Disease Optivate - Von Willebrand Disease | Phase 3 | Terminated | Bio Products Laboratory | 26 | 2006-11-01 | 2010-03-03 |
| A Study to Compare the Pharmacokinetics and Safety of Optivate® and Haemate P® in Patients With Von Willebrand Disease. Optivate® (Human Coagulation Factor VIII), Haemate P® (Human Coagulation Factor VIII) - vonWillebrand's Disease | Phase 2 | Completed | Bio Products Laboratory | 2004-12-01 | 2018-02-15 | |
| A Study to Investigate the Safety and Efficacy of Optivate® in Children Under 6 Years of Age With Haemophilia A. Optivate® (Human Coagulation Factor VIII) - Haemophilia A | Phase 3 | Completed | Bio Products Laboratory | 2003-11-01 | 2018-02-15 | |
| An Open Study to Investigate the Safety and Efficacy of Optivate® in Haemophilia A Patients Undergoing Surgery. Optivate® (Human Coagulation Factor VIII) - Haemophilia A | Phase 3 | Completed | Bio Products Laboratory | 2001-11-01 | 2018-02-15 | |
| A Study to Compare the Pharmacokinetics and Safety of Current Factor VIII Concentrate and Optivate® in Haemophilia A. Optivate® (Human Coagulation Factor VIII) - Von Willebrand Disease | Phase 3 | Completed | Bio Products Laboratory | 2001-10-01 | 2018-02-15 | |
| An Open Study to Investigate the Safety and Efficacy of Optivate® in Severe Haemophilia A Patients. Optivate® (Human Coagulation Factor VIII) - Haemophilia A | Phase 3 | Completed | Bio Products Laboratory | 2001-09-01 | 2018-02-15 |
Hemophilia A (7) · von Willebrand Diseases (3)
Bio Products Laboratory (8) · City of Hope Medical Center (2)
Poland (5) · United Kingdom (5) · Israel (3) · Colombia (1) · Germany (1) · United States (1)
Charles Hay, MD (1) · Eric Wolford (1) · Nadia P Ewing, MD (1) · Nadia P. Ewing, MD (1) · Thynn Thynn Yee (1)
2008 (2)