5 completed. 5 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 5 |
| Phase 3 | 1 | Completed 1 |
Follow olesoxime: new trials by email Literature Review of olesoxime trials Research Report on olesoxime
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate Long Term Safety, Tolerability, and Effectiveness of Olesoxime in Patients With Spinal Muscular Atrophy (SMA) Olesoxime - Muscular Atrophy, Spinal | Phase 2 | Completed | Hoffmann-La Roche | 131 | 2016-01-20 | 2019-08-09 |
| Safety and Efficacy of Olesoxime (TRO19622) in 3-25 Years SMA Patients. Olesoxime, Placebo - Spinal Muscular Atrophy Type II, Spinal Muscular Atrophy Type III Non Ambulant | Phase 2 | Completed | Hoffmann-La Roche | 165 | 2010-11-01 | 2016-11-22 |
| Safety Extension Study of TRO19622 in ALS TRO19622 - Amyotrophic Lateral Sclerosis | Phase 2 / Phase 3 | Completed | Hoffmann-La Roche | 271 | 2010-10-01 | 2016-11-22 |
| Effect of TRO19622 in the Treatment of Patients With Chemotherapy Induced Peripheral Neuropathy Olesoxime (TRO19622), Placebo Control - Chemotherapy-Induced Peripheral Neuropathy | Phase 2 | Completed | Hoffmann-La Roche | 17 | 2009-03-01 | 2016-11-22 |
| Exploratory Study to Assess the Short Term Effect on Liver Enzymes and the Safety of TRO19622 in Patients With Non-Alcoholic Steatohepatitis (NASH) TRO19622, Placebo - Non-Alcoholic Steatohepatitis (NASH) | Phase 2 | Completed | Hoffmann-La Roche | 22 | 2008-04-15 | 2025-12-18 |
Amyotrophic Lateral Sclerosis (1) · Muscular Atrophy, Spinal (1) · Non-alcoholic Fatty Liver Disease (1) · Spinal Muscular Atrophies of Childhood (1)
France (5) · Belgium (3) · Germany (3) · United Kingdom (3) · Italy (2) · Netherlands (2) · Poland (2) · Spain (1)
Enrico Bertini, MD (1) · Ivan Krakowski, MD (1) · Vincent Meininger, MD, PhD (1) · Vlad Ratziu, MD (1)
2015 (1)