4 completed, 2 terminated, 2 withdrawn, 1 unknown. 3 Phase 3, 3 Phase 4, 2 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 3 | Terminated 1, Unknown 1, Withdrawn 1 |
| Phase 4 | 3 | Completed 2, Terminated 1 |
| Phase 1 | 2 | Completed 1, Withdrawn 1 |
| Phase 2 | 1 | Completed 1 |
Follow nomegestrol acetate: new trials by email Literature Review of nomegestrol acetate trials Research Report on nomegestrol acetate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Use of Nomegestrol Acetate/Estradiol in Random Start Rapid Endometrial Preparation Nomegestrol Acetate/Estradiol 2.5mg/1.5mg - Endometrial Polyp, Endometrial Diseases | Phase 4 | Completed | University of Palermo | 80 | 2023-01-01 | 2024-04-08 |
| The Use of Drospirenone/Estetrol, Nomegestrol Acetate/Estradiol and Ethinylestradiol/Dienogest in Random Start Rapid Endometrial Preparation Drospirenone / Estetrol, Nomegestrol Acetate / Estradiol, Ethinylestradiol / Dienogest - Endometrial Polyp, Endometrial Diseases | Phase 4 | Completed | University of Palermo | 150 | 2023-01-01 | 2024-04-08 |
| Contraceptive Efficacy and Safety of NOMAC-E2 Combined Oral Contraceptive NOMAC-E2 COC - Contraception | Phase 3 | Terminated | Organon and Co | 3055 | 2022-02-17 | 2025-11-21 |
| Bioequivalence of Two Fixed-dose Combination Tablets Containing Estradiol and Nomegestrol Acetate Estradiol 1.5 mg/nomegestrol acetate 2.5 mg (Reference Product), Estradiol 1.5 mg/nomegestrol acetate 2.5 mg (Test Product) - Bioequivalence | Phase 1 | Withdrawn | Grünenthal GmbH | 2019-10-01 | 2019-07-15 | |
| Comparison of Coagulation Profiles Between Zoely and Minidoz: RCT 1.5 mg estradiol and 2.5 mg nomegestrol acetate, 15 µg ethinylestradiol and 60 µg gestodene - Contraception, Hypercoagulability | Phase 4 | Terminated | Mahidol University | 112 | 2016-03-01 | 2018-05-21 |
| Efficacy and Safety of Oral NOMAC-E2 in Indian Women (P07057/MK-8175A-017) Nomegestrol acetate (NOMAC), Estradiol (E2) - Contraception | Phase 3 | Withdrawn | Organon and Co | 2013-07-01 | 2022-02-16 | |
| A Dose-Finding Study to Evaluate Ovarian Function and Vaginal Bleeding in Next Generation Rings (P06109/MK-8175A/MK-8342B-012) Nomegestrol acetate (NOMAC), Etonogestrel (ENG), Ethinyl estradiol (EE) - Contraception | Phase 2 | Completed | Organon and Co | 666 | 2012-12-12 | 2024-05-28 |
| A Trial to Assess the Pharmacokinetic Profile (e.g., Uptake, Distribution and Excretion of a Substance in the Body) of Nomegestrol Acetate (NOMAC), Estradiol (E2) and Estrone (E1) After Multiple and Single Dose Administration of the Combined Oral Contraception NOMAC-E2 (COMPLETED)(P05822) nomegestrol acetate and estradiol - Healthy | Phase 1 | Completed | Organon and Co | 25 | 2007-05-01 | 2022-02-03 |
| POPART'MUS: Prevention of Post Partum Relapses With Progestin and Estradiol in Multiple Sclerosis nomegestrol acetate, estradiol, placebo - Multiple Sclerosis | Phase 3 | Unknown | Hospices Civils de Lyon | 300 | 2005-06-01 | 2011-12-30 |
Uterine Diseases (2) · Multiple Sclerosis (1) · Thrombophilia (1)
Organon and Co (4) · University of Palermo (2) · Grünenthal GmbH (1) · Hospices Civils de Lyon (1) · Mahidol University (1)
Italy (2) · France (1) · Mexico (1) · United States (1)