5 completed. 3 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 3 |
| Phase 1 | 2 | Completed 2 |
Follow MEDI-545: new trials by email Literature Review of MEDI-545 trials Research Report on MEDI-545
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate the Efficacy and Safety of Sifalimumab in Adults With Systemic Lupus Erythematosus Sifalimumab 200 mg, Sifalimumab 600 mg, Sifalimumab 1,200 mg - Systemic Lupus Erythematosus | Phase 2 | Completed | MedImmune LLC | 834 | 2011-03-31 | 2018-04-19 |
| A Study to Evaluate Safety and Tolerability of IV or SC Dose of MEDI-545 in Patients With Systemic Lupus Erythematosus. MEDI-545, MEDI-545 600 - Systemic Lupus Erythematosus | Phase 2 | Completed | AstraZeneca | 30 | 2009-11-25 | 2018-11-19 |
| A Study to Evaluate Safety and Tolerability of Subcutaneous Doses of MEDI-545 in Subjects With Lupus MEDI-545, Placebo - Lupus Erythematosus, Systemic, Lupus | Phase 2 | Completed | MedImmune LLC | 87 | 2008-07-01 | 2016-08-09 |
| A Study to Evaluate Safety of Multi-Dose MEDI-545 in Adult Patients With Dermatomyositis or Polymyositis MEDI-545, Placebo - DERMATOMYOSITIS OR POLYMYOSITIS | Phase 1 | Completed | MedImmune LLC | 51 | 2008-04-01 | 2012-05-28 |
| Safety and Tolerability of MEDI-545 in Patients Who Have Systemic Lupus Erythematosus (SLE) MEDI-545, MEDI 545 - Lupus | Phase 1 | Completed | MedImmune LLC | 45 | 2006-03-01 | 2007-12-18 |
Lupus Erythematosus, Systemic (3) · Autoimmune Diseases (1) · Dermatomyositis (1) · Immune System Diseases (1)
MedImmune LLC (4) · AstraZeneca (1)
United States (4) · Canada (2) · Argentina (1) · Brazil (1) · Bulgaria (1) · Chile (1) · France (1) · Germany (1) · Hungary (1) · India (1) · Italy (1) · Jamaica (1) · Japan (1) · Mexico (1) · Netherlands (1)
Barbara White, M.D. (1) · Dominique Ethgen, M.D. (1) · Gabor Illei, MD (1) · Tsutomu Takeuchi (1) · Warren Greth, M.D. (1) · Yoshiya Tanaka (1)
PMID 21798883, PMID 33687069, PMID 19479852, PMID 23434567, PMID 31660791