6 completed. 3 Phase 3, 1 Not applicable, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 3 | Completed 3 |
| Not applicable | 1 | Completed 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
Follow macimorelin: new trials by email Literature Review of macimorelin trials Research Report on macimorelin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Research Study of How Well Macimorelin Works to Find Out if Children Have a Lack of Growth Hormone and How Safe it is Macimorelin, Arginine, Clonidine - Growth Hormone Deficiency | Phase 3 | Completed | AEterna Zentaris | 101 | 2021-11-16 | 2024-08-12 |
| Copeptin After an Oral Stimulation With Macimorelin in Healthy Volunteers Macimorelin 0.5mg/kg body weight, Macimorelin 0.75mg/kg body weight - Polyuria-polydipsia Syndrome | Not applicable | Completed | University Hospital, Basel, Switzerland | 28 | 2019-03-07 | 2019-08-08 |
| Validation of Macimorelin as a Test for Adult Growth Hormone Deficiency Macimorelin, Insulin - Growth Hormone Deficiency With Pituitary Anomalies | Phase 3 | Completed | AEterna Zentaris | 157 | 2015-12-03 | 2018-04-10 |
| Pilot Clinical Trial of Repeated Doses of Macimorelin to Assess Safety and Efficacy in Patients With Cancer Cachexia Macimorelin, Placebo - Cancer Cachexia | Phase 2 | Completed | Garcia, Jose M., MD, PhD | 15 | 2012-05-01 | 2024-03-20 |
| Investigation of a New, Oral Growth Hormone Secretagogue, AEZS-130 as a Growth Hormone Stimulation Test. AEZS-130 (formerly ARD-07), L-ARG+GHRH - Diagnosis of Adult Growth Hormone Deficiency (AGDH) | Phase 3 | Completed | AEterna Zentaris | 101 | 2007-06-01 | 2019-07-23 |
| Oral Ghrelin Agonist in Healthy Subjects EP1572 (ghrelin agonist) oral and duodenal application - Healthy Subjects | Phase 1 | Completed | University Hospital, Basel, Switzerland | 42 | 2005-11-01 | 2007-05-03 |
Dwarfism, Pituitary (2) · Diabetes Insipidus (1) · Growth Hormone Deficiency With Pituitary Anomalies (1)
AEterna Zentaris (3) · University Hospital, Basel, Switzerland (2) · Garcia, Jose M., MD, PhD (1)
United States (4) · Germany (2) · Italy (2) · Poland (2) · Serbia (2) · Armenia (1) · Austria (1) · France (1) · Georgia (1) · Romania (1) · Slovakia (1) · Slovenia (1) · Spain (1) · Switzerland (1) · Turkey (Türkiye) (1)
Beverly MK Biller, MD (1) · Christoph Beglinger (1) · Jose M Garcia, MD PhD (1) · Jose M Garcia, MD, PhD (1) · Mirjam Christ-Crain, Prof. Dr. MD (1) · Nicola K Ammer, MD (1)
PMID 17284637, PMID 23559086, PMID 29575771, PMID 29860473, PMID 33615399, PMID 36860137
2018 (2), 2015 (1)