5 completed. 5 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 5 |
Follow Lumefantrine: new trials by email Literature Review of Lumefantrine trials Research Report on Lumefantrine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Efavirenz Ganaplacide, Lumefantrine, Efavirenz - Malaria | Phase 1 | Completed | Novartis Pharmaceuticals | 14 | 2022-04-28 | 2023-01-12 |
| Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Midazolam, Repaglinide, Dextromethorphan, Metformin, Rosuvastatin and Dolutegravir Midazolam, Repaglinide, Dextromethorphan - Malaria | Phase 1 | Completed | Novartis Pharmaceuticals | 48 | 2022-03-09 | 2022-11-04 |
| Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Itraconazole Ganaplacide, Lumefantrine, Itraconazole - Malaria | Phase 1 | Completed | Novartis Pharmaceuticals | 19 | 2021-11-18 | 2022-10-28 |
| Safety, Immunogenicity, and Protective Efficacy of Two Regimens of Radiation Attenuated Plasmodium Falciparum NF54 Sporozoites (PfSPZ Vaccine) During Natural Transmission Season in Healthy African Adults in Mali PfSPZ Vaccine, Normal Saline, artemether 20mg/lumefantrine 120mg (AL) - Malaria | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 478 | 2018-05-14 | 2021-08-20 |
| Effect of ACT-451840 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Subjects ACT-451840:, Plasmodium falciparum-infected human erythrocytes:, Artemether 20 mg and lumefantrine 120mg combination tablet: - Healthy Subjects | Phase 1 | Completed | Idorsia Pharmaceuticals Ltd. | 8 | 2014-06-01 | 2019-08-22 |
Malaria (5) · Malaria, Falciparum (1)
Novartis Pharmaceuticals (3) · Idorsia Pharmaceuticals Ltd. (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1)
United Kingdom (3) · Australia (1) · Mali (1)
Michelle Lee (1) · Patrick E Duffy, M.D. (1)