2 completed, 1 active not recruiting, 1 recruiting, 1 unknown. 4 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 4 | Completed 2, Recruiting 1, Unknown 1 |
| Phase 2 | 1 | Active not recruiting 1 |
Follow lonapegsomatropin: new trials by email Literature Review of lonapegsomatropin trials Research Report on lonapegsomatropin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Trial Investigating the Efficacy and Safety of Weekly Lonapegsomatropin Compared to Daily Somatropin in Children and Adolescents With Short Stature or Growth Failure Due to Growth Hormone Sufficient Disorders Lonapegsomatropin [SKYTROFA®], Somatropin Pen Injector - Turner Syndrome, Short Stature Homeobox Gene Mutation | Phase 3 | Recruiting | Ascendis Pharma A/S | 186 | 2025-12-12 | 2026-09-30 |
| A Trial to Investigate Different Doses of Lonapegsomatropin Compared to Somatropin in Individuals With Turner Syndrome Lonapegsomatropin, Somatropin - Turner Syndrome | Phase 2 | Active not recruiting | Ascendis Pharma Endocrinology Division A/S | 48 | 2023-02-15 | 2026-05-13 |
| A Trial to Investigate Long Term Efficacy and Safety of Lonapegsomatropin in Adults With Growth Hormone Deficiency Lonapegsomatropin - Adult Growth Hormone Deficiency, Endocrine System Diseases | Phase 3 | Completed | Ascendis Pharma Endocrinology Division A/S | 220 | 2021-12-16 | 2026-07-07 |
| A Trial to Compare the Efficacy and Safety of Once-weekly Lonapegsomatropin With Placebo and a Daily Somatropin Product in Adults With Growth Hormone Deficiency Lonapegsomatropin, Placebo, Somatropin - Growth Hormone Deficiency, Endocrine System Diseases | Phase 3 | Completed | Ascendis Pharma Endocrinology Division A/S | 264 | 2020-12-03 | 2026-07-07 |
| Safety, Tolerability and Efficacy of TransCon hGH Weekly Versus Daily hGH in Chinese Pediatric Growth Hormone Deficiency TransCon hGH, daily hGH - Growth Hormone Deficiency, Endocrine System Diseases | Phase 3 | Unknown | Visen Pharmaceuticals (Shanghai) Co., Ltd. | 150 | 2019-12-30 | 2020-03-30 |
Endocrine System Diseases (4) · Dwarfism, Pituitary (3) · Failure to Thrive (2) · Turner Syndrome (2) · Chromosome Disorders (1) · Dwarfism (1) · Noonan Syndrome (1) · Pituitary Diseases (1) · Sex Chromosome Disorders (1) · Sex Chromosome Disorders of Sex Development (1)
Ascendis Pharma Endocrinology Division A/S (3) · Ascendis Pharma A/S (1) · Visen Pharmaceuticals (Shanghai) Co., Ltd. (1)
United States (4) · France (3) · Germany (3) · Italy (3) · Romania (3) · South Korea (3) · Spain (3) · Armenia (2) · Australia (2) · Canada (2) · Georgia (2) · Greece (2) · Israel (2) · Japan (2) · Malaysia (2)
Xiaoping Luo, MD (1)