6 terminated. 6 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Terminated 6 |
| Phase 2 | 4 | Terminated 4 |
Follow Lomustine: new trials by email Literature Review of Lomustine trials Research Report on Lomustine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Selinexor in Combination With Standard of Care Therapy for Newly Diagnosed or Recurrent Glioblastoma Selinexor, Temozolomide (TMZ), Lomustine (CCNU) - Glioblastoma Multiforme | Phase 1 / Phase 2 | Terminated | Karyopharm Therapeutics Inc | 74 | 2020-06-08 | 2024-12-16 |
| Study to Evaluate Safety, Tolerability, and Optimal Dose of Candidate GBM Vaccine VBI-1901 in Recurrent GBM Subjects VBI-1901, Carmustine, Lomustine - Glioblastoma Multiforme | Phase 1 / Phase 2 | Terminated | VBI Vaccines Inc. | 70 | 2017-12-06 | 2026-05-08 |
| Phase 1/2 Study of USL311 +/- Lomustine in Advanced Solid Tumors or Relapsed/Recurrent Glioblastoma Multiforme (GBM) USL311, Lomustine - Solid Tumors (Phase 1), Relapsed/Recurrent GBM (Phase 2) | Phase 1 / Phase 2 | Terminated | Proximagen, LLC | 26 | 2016-04-01 | 2021-07-23 |
| Ph 1/2 CTO With Lomustine for Bevacizumab-Naive Recurrent Glioma CTO, Lomustine - Malignant Glioma (WHO Grade III or IV) | Phase 1 | Terminated | Annick Desjardins | 9 | 2014-05-01 | 2016-08-04 |
| A Clinical Trial to Assess the Safety & Efficacy of the Treatment of Patients With Metastasis From Malignant Melanoma - Treatment Consists of the Substances Lomustine (Capsules) & Cytarabine (Injected Into an Area Near the Spinal Cord), Accompanied by Radiotherapy of the Brain Brain radiotherapy (WBRT alone, SRT/SRS alone or WBRT plus SRT/SRS), Lomustine, Liposomal cytarabine - Leptomeningeal Metastasis From Malignant Melanoma | Phase 1 | Terminated | University Hospital, Bonn | 1 | 2012-03-01 | 2016-04-19 |
| Study of CCNU (Lomustine) Plus Dasatinib in Recurrent Glioblastoma (GBM) Dasatinib, Lomustine - Glioblastoma | Phase 1 / Phase 2 | Terminated | Bristol-Myers Squibb | 28 | 2009-10-01 | 2012-08-31 |
Glioblastoma (4) · Neoplasms (2) · Brain Neoplasms (1) · Glioma (1) · Lymphoma, Follicular (1) · Recurrence (1)
Annick Desjardins (1) · Bristol-Myers Squibb (1) · Karyopharm Therapeutics Inc (1) · Proximagen, LLC (1) · University Hospital, Bonn (1) · VBI Vaccines Inc. (1)
United States (4) · Canada (1) · France (1) · Germany (1) · Italy (1) · Netherlands (1) · Spain (1) · Switzerland (1)
Andrew B Lassman, MD (1) · Annick Desjardins, MD, FRCPC (1) · Francisco Diaz-Mitoma, MD (1) · Martin Glas, PD Dr. (1) · Tze-Chiang Meng, MD (1)
2009 (1)