6 completed, 1 not yet recruiting, 1 terminated, 1 unknown. 9 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 9 | Completed 6, Not yet recruiting 1, Terminated 1, Unknown 1 |
| Phase 2 | 4 | Completed 1, Not yet recruiting 1, Terminated 1, Unknown 1 |
Follow Jaktinib: new trials by email Literature Review of Jaktinib trials Research Report on Jaktinib
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Jaktinib for Steroid-Refractory Acute Graft-Versus-Host Disease Jaktinib - Acute Graft vs Host Disease | Phase 1 / Phase 2 | Not yet recruiting | Nanfang Hospital, Southern Medical University | 49 | 2026-10-10 | 2026-10-21 |
| A Study to Evaluate the Effect of Jaktinib on QT/QTc Interval in Healthy Participants Jaktinib, Placebo - Healthy Participants | Phase 1 | Completed | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 32 | 2024-03-19 | 2024-12-12 |
| Comparative Study on Pharmacokinetics of Two Formulations of Jaktinib in Healthy Adults Under Fasting Conditions Jaktinib Hydrochloride Tablets - Myelofibrosis | Phase 1 | Completed | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 52 | 2023-11-29 | 2024-01-11 |
| A Study to Evaluate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics of Jaktinib in Healthy Volunteers Jaktinib Hydrochloride Tablets, Itraconazole capsule, Rifampicin Capsules - Healthy Volunteers | Phase 1 | Completed | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 40 | 2021-10-27 | 2024-02-07 |
| Jaktinib and Azacitidine In Treating Patients With MDS With MF or MDS/MPN With MF. Jaktinib, azacitidine - Myelodysplastic Syndromes, Myeloproliferative Neoplasms | Phase 1 / Phase 2 | Terminated | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 1 | 2021-09-30 | 2022-12-01 |
| Pharmacokinetics Of Jaktinib In Subjects With Hepatic Impairment And Normal Hepatic Function Jaktinib Hydrochloride Tablets - Hepatic Insufficiency, Healthy Subjects | Phase 1 | Completed | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 24 | 2021-08-27 | 2024-01-11 |
| Jaktinib Hydrochloride Cream For Atopic Dermatitis Jaktinib Hydrochloride Cream, Placebo - Atopic Dermatitis | Phase 1 / Phase 2 | Completed | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 107 | 2020-10-14 | 2024-04-02 |
| A Study With Jaktinib Hydrochloride Cream Applied Topically to Subjects With Alopecia Areata Jaktinib hydrochloride cream, Placebo - Alopecia Areata(AA) | Phase 1 / Phase 2 | Unknown | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 160 | 2020-08-12 | 2024-03-06 |
| The Tolerance, Pharmacokinetics of Jaktinib in Healthy Volunteers Jaktinib Dihydrochloride Monohydrate, placebo - Healthy Volunteers | Phase 1 | Completed | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 126 | 2017-09-28 | 2019-03-01 |
Primary Myelofibrosis (2) · Alopecia Areata (1) · Dermatitis, Atopic (1) · Hepatic Insufficiency (1) · Myelodysplastic Syndromes (1) · Myeloproliferative Disorders (1)
Suzhou Zelgen Biopharmaceuticals Co.,Ltd (8) · Nanfang Hospital, Southern Medical University (1)
China (9)
Jason Wu (2) · LiYan Miao (1) · Liyan Miao, PhD (1) · Qianjin Lu, PhD (1) · Weifeng Zhao, PhD (1) · Yanhua Ding, MD (1)