4 completed, 2 terminated, 1 active not recruiting. 5 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 3, Terminated 2 |
| Phase 3 | 1 | Completed 1 |
Follow Hemin: new trials by email Literature Review of Hemin trials Research Report on Hemin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Panhematin for Prevention of Acute Attacks of Porphyria Hemin for injection, Placebo - Acute Intermittent Porphyria, Hereditary Coproporphyria | Phase 2 | Terminated | The University of Texas Medical Branch, Galveston | 13 | 2015-10-30 | 2026-01-30 |
| Controlled Trial of Panhematin in Treatment of Acute Attacks of Porphyria Panhematin, Glucose - Acute Porphyrias | Phase 2 | Completed | The University of Texas Medical Branch, Galveston | 20 | 2014-04-28 | 2025-04-11 |
| Acute Porphyria Biomarkers for Disease Activity Hemin - Acute Intermittent Porphyria, Hereditary Coproporphyria | Active not recruiting | The University of Texas Medical Branch, Galveston | 50 | 2014-04-28 | 2026-05-12 | |
| Hemin to Prevent Post-ERCP (Endoscopic Retrograde Cholangiopancreatography) Acute Pancreatitis Hemin, placebo - Post-ERCP Acute Pancreatitis | Phase 2 | Completed | Erasme University Hospital | 284 | 2012-04-01 | 2021-07-07 |
| Induction of HO-1; a Therapeutic Approach to Reduce Ischaemia Reperfusion Injury (IRI) Following Deceased Donor Renal Transplantation Heme arginate (Normosang), 0.9% sodium chloride - Graft Failure, Ischemia-reperfusion Injury | Phase 3 | Completed | University of Edinburgh | 40 | 2012-01-01 | 2015-05-27 |
| A Pilot Study of Hemin Therapy for Gastroparesis (Diabetes Mellitus) Hemin, Albumin - Gastroparesis, Diabetes Mellitus | Phase 2 | Completed | Mayo Clinic | 20 | 2010-05-01 | 2016-02-04 |
| Phase 2, Open-Label, Multi-Dose Study of Panhematin in Patients With MDS Panhematin - Myelodysplastic Syndrome | Phase 2 | Terminated | Rush University Medical Center | 6 | 2007-05-01 | 2014-10-24 |
Porphyria, Acute Intermittent (3) · Coproporphyria, Hereditary (2) · Porphyria, Variegate (2) · Porphyrias (2) · Diabetes Mellitus (1) · Gastroparesis (1) · Myelodysplastic Syndromes (1) · Reperfusion Injury (1)
The University of Texas Medical Branch, Galveston (3) · Erasme University Hospital (1) · Mayo Clinic (1) · Rush University Medical Center (1) · University of Edinburgh (1)
United States (5) · Belgium (1) · Taiwan (1) · United Kingdom (1)
Karl E Anderson, MD (2) · Adil E Bharucha, MBBS, MD (1) · Arnaud Lemmers, MD,PhD (1) · David Kluth, PhD (1) · Jamile Shammo, MD (1) · Karl E Anderson (1) · Lorna Marson, MD (1) · Rachel Thomas, MBChB (1) · Stephen McNally, PhD (1)
PMID 42833135, PMID 26680374, PMID 38431445
P01DK068055 (1), UL1TR000135 (1)