3 completed, 1 not yet recruiting. 3 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 3 |
| Phase 2 | 1 | Not yet recruiting 1 |
Follow Genes, env: new trials by email Literature Review of Genes, env trials Research Report on Genes, env
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating the Safety and Immunogenicity of Polyvalent DNA and Recombinant gp120 Protein HIV Vaccine (PDPHV) in Healthy, HIV-uninfected Adults PDPHV Plasmid DNA Vaccines (env (A, B, C, A/E)/gag (C)), PDPHV Recombinant Protein Vaccines (gp120 (A, B, C, A/E)), Alhydrogel adjuvant - HIV Prevention | Phase 2 | Not yet recruiting | Worcester HIV Vaccine | 126 | 2026-09-01 | 2026-06-30 |
| Evaluating the Safety and Immunogenicity of Polyvalent DNA/gp120 HIV Vaccine in Healthy, HIV-uninfected Adults env (A,B,C,A/E)/gag (C) DNA Vaccine, gp120 (A,B,C,A/E) Protein Vaccine, GLA-SE adjuvant - HIV Infections | Phase 1 | Completed | Worcester HIV Vaccine | 42 | 2021-07-08 | 2024-04-09 |
| Evaluating the Safety and Immunogenicity of Env (A,B,C,A/E)/Gag (C) DNA and gp120 (A,B,C,A/E) Protein/GLA-SE HIV Vaccines, Given Individually or Co-administered, in Healthy, HIV-1-Uninfected Adults env (A,B,C,A/E)/gag (C) DNA Vaccine, gp120 (A,B,C,A/E) Protein Vaccine, Placebo - HIV Infections | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 60 | 2018-03-16 | 2022-04-25 |
| Evaluating the Safety, Tolerability, and Immunogenicity of a Prime-Boost Regimen of HIV-1 Nef/Tat/Vif, Env pDNA Vaccine Delivered Intramuscularly With Electroporation and HIV-1 rVSV envC Vaccine in Healthy, HIV-Uninfected Adults HIV-1 nef/tat/vif, env pDNA vaccine, rVSV HIV envC vaccine, Placebo - HIV Infections | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 14 | 2016-03-01 | 2021-10-15 |
HIV Infections (3)
National Institute of Allergy and Infectious Diseases (NIAID) (2) · Worcester HIV Vaccine (2)
United States (4) · South Africa (1)
Conasagrie Nair, PhD, MD (1) · Greg Wilson (1) · Ian Frank (1) · Stephen Walsh, PhD, MD (1) · Turner Overton (1)