FHD-286: Clinical Trials

4 trials of FHD-286, newest first

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2 recruiting, 1 active not recruiting, 1 terminated. 3 Phase 1, 1 Phase 2.

By phase and status

PhaseTrialsStatus
Phase 13Active not recruiting 1, Recruiting 1, Terminated 1
Phase 21Recruiting 1

Follow FHD-286: new trials by email Literature Review of FHD-286 trials Research Report on FHD-286

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
SMARCA4/2 Inhibitor for POU2F3-Positive SCLC
FHD-286 - Small Cell Lung Cancer
Phase 2RecruitingDana-Farber Cancer Institute202026-04-282026-10-26
FHD-286 With Low-Dose Weekly Decitabine/Venetoclax in Patients With Acute Myeloid Leukemia
Decitabine, Venetoclax, FHD-286 - Acute Myeloid Leukemia, Myelodysplastic Syndrome
Phase 1RecruitingMontefiore Medical Center332026-02-032026-03-03
FHD-286 as Monotherapy or Combination Therapy in Subjects With Advanced Hematologic Malignancies
FHD-286, Low Dose Cytarabine, Decitabine - Advanced Hematologic Malignancy, Relapsed Acute Myeloid Leukemia
Phase 1Active not recruitingFoghorn Therapeutics Inc.1442021-06-142025-07-10
FHD-286 in Subjects With Metastatic Uveal Melanoma
FHD-286 - Metastatic Uveal Melanoma
Phase 1TerminatedFoghorn Therapeutics Inc.762021-05-112024-04-25

Conditions studied

Leukemia, Myeloid, Acute (2)  ·  Myelodysplastic Syndromes (2)  ·  Leukemia, Myelomonocytic, Chronic (1)  ·  Small Cell Lung Carcinoma (1)  ·  Uveal Melanoma (1)

Sponsors

Foghorn Therapeutics Inc. (2)  ·  Dana-Farber Cancer Institute (1)  ·  Montefiore Medical Center (1)

Countries

United States (4)  ·  France (1)  ·  Netherlands (1)

Top investigators

Sarah Reilly, MD (2)  ·  Alissa Cooper (1)  ·  Mendel R Goldfinger, MD (1)

Results publications

PMID 40238563

NIH funding

2025 (1)