3 completed, 1 active not recruiting, 1 unknown. 5 Phase 2, 3 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 3, Active not recruiting 1, Unknown 1 |
| Phase 3 | 3 | Completed 2, Active not recruiting 1 |
| Phase 1 | 1 | Completed 1 |
Follow Elaprase: new trials by email Literature Review of Elaprase trials Research Report on Elaprase
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Extension Study of Idursulfase-IT Along With Elaprase in Children and Adults With Hunter Syndrome and Cognitive Impairment Idursulfase-IT, Elaprase - Hunter Syndrome | Phase 2 / Phase 3 | Active not recruiting | Takeda | 6 | 2024-03-05 | 2025-11-06 |
| Study of Idursulfase-beta (GC1111) in Hunter Syndrome idursulfase beta, idursulfase - Mucopolysaccharidosis II | Phase 2 | Unknown | Green Cross Corporation | 20 | 2016-12-01 | 2016-01-26 |
| Study of Long Term Safety and Clinical Outcomes of Idursulfase IT and Elaprase Treatment in Pediatric Participants Who Have Completed Study HGT-HIT-094 Idursulfase-IT, Elaprase - Hunter Syndrome | Phase 2 / Phase 3 | Completed | Shire | 56 | 2015-04-14 | 2025-06-19 |
| An Extension Study of HGT-HIT-045 Evaluating Long-Term Safety and Clinical Outcomes of Idursulfase-IT in Conjunction With Elaprase in Pediatric Participants With Hunter Syndrome and Cognitive Impairment Idursulfase-IT, Elaprase - Hunter Syndrome | Phase 1 / Phase 2 | Completed | Takeda | 15 | 2010-08-01 | 2025-08-06 |
| Iduronate-2-sulfatase Enzyme Replacement Therapy in Mucopolysaccharidosis II (MPS II) Iduronate-2-sulfatase enzyme replacement therapy, iduronate-2-sulfatase enzyme replacement therapy, Placebo - Mucopolysaccharidosis II | Phase 2 / Phase 3 | Completed | Shire | 96 | 2003-09-18 | 2021-06-10 |
Mucopolysaccharidosis II (5) · Sudden Infant Death (2) · Lysosomal Storage Diseases (1)
Shire (2) · Takeda (2) · Green Cross Corporation (1)
Canada (3) · United Kingdom (3) · United States (3) · France (2) · Australia (1) · Brazil (1) · Germany (1) · Mexico (1) · Spain (1)
PMID 23837440, PMID 33874971, PMID 35588317, PMID 35961250, PMID 37915038
2014 (1), 2023 (1)