4 unknown, 3 completed, 3 recruiting, 1 active not recruiting. 13 Phase 2, 3 Phase 1, 3 Phase 3.
Follow EC regimen: new trials by email Literature Review of EC regimen trials Research Report on EC regimen
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of First-line Treatment for Extensive-stage Small Cell Lung Cancer Using a Combination Therapy of Trilaciclib, Envafolimab, Etoposide, and Carboplatin Chemotherapy （Etoposide and Carboplatin）, Immunotherapy （Envafolimab）, Trilaciclib - Lung Cancer, Small Cell | Phase 2 | Recruiting | Shanghai Chest Hospital | 52 | 2024-10-13 | 2024-11-21 |
| Adebrelimab and Concurrent Radiochemotherapy as First-line Treatment for Extensive-stage Small-cell Lung Cancer Adebrelimab, Radiation Therapy, etoposide, carboplatin(EC) - Small Cell Lung Carcinoma | Phase 2 | Not yet recruiting | Henan Cancer Hospital | 48 | 2024-02-10 | 2024-02-01 |
| A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study) Peluntamig (PT217), Carboplatin + Etoposide, Paclitaxel. - Small Cell Lung Cancer (SCLC), Large Cell Neuroendocrine Cancer (LCNEC) | Phase 1 / Phase 2 | Recruiting | Phanes Therapeutics | 203 | 2023-09-05 | 2026-07-15 |
| Neoadjuvant Fluzoparib in Germline BRCA-mutated Three-negative Breast Cancer Breast Cancer Fluzoparib+Paclitaxel, Epirubicin+Cyclophosphamide - TNBC - Triple-Negative Breast Cancer | Phase 2 | Unknown | The First Affiliated Hospital with Nanjing Medical University | 60 | 2023-04-08 | 2023-04-28 |
| The Efficacy of WVI in Patients With Localized Basal Ganglia Intracranial Germ Cell Tumors Whole-ventricle irradiation, Carboplatin/etoposide, Ifosfamide/cisplatin/etoposide - Intracranial Germ Cell CNS Tumor, Childhood | Phase 2 | Recruiting | Beijing Tiantan Hospital | 150 | 2021-09-15 | 2021-11-18 |
| This Phase II/III, Multicenter Study is Designed to Evaluate the Safety and Clinical Activity of AL3810 in Patients AL3810, carboplatin + etoposide, Placebo - Extensive-stage Small Cell Lung Cancer | Phase 2 / Phase 3 | Unknown | Haihe Biopharma Co., Ltd. | 313 | 2019-11-14 | 2020-02-05 |
| Safety and Efficacy of FOLFSIM Plus Toripalimab in the Treatment of Advanced or Metastatic Neuroendocrine Carcinoma Simmtecan, 5-FU and l-LV, Toripalimab, Etoposide, Cisplatin - Neuroendocrine Carcinoma of the Bladder | Phase 2 / Phase 3 | Unknown | Peking University | 336 | 2019-06-19 | 2019-06-20 |
| Adjuvant Palbociclib in Elderly Patients With Breast Cancer Palbociclib, Docetaxel / cyclophosphamide, doxorubicin/cyclophosphamide - Breast Cancer Stage II, Breast Cancer Stage III | Phase 2 | Active not recruiting | European Organisation for Research and Treatment of Cancer - EORTC | 366 | 2019-06-14 | 2026-05-12 |
| Study of Sequential High-dose Chemotherapy in Children With High Risk Medulloblastoma Carboplatin + etoposide, Thiotepa, Cyclophosphamide + Busilvex - High-risk Medulloblastoma | Phase 1 / Phase 2 | Terminated | Gustave Roussy, Cancer Campus, Grand Paris | 29 | 2013-09-14 | 2024-05-24 |
| A Study of Pegylated Liposomal Doxorubicin and Cyclophosphamide in Her2-negative Stage I and II Breast Cancer Patients Epirubicin+Cyclophosphamide, liposomal-doxorubicin+Cyclophosphamide - Breast Cancer | Phase 2 | Unknown | TTY Biopharm | 254 | 2010-06-01 | 2021-11-23 |
| Etoposide-Carboplatin Alone or With Endostar for Extensive Disease Small Cell Lung Cancer (ED-SCLC) Endostar, Etoposide-Carboplatin - Small Cell Lung Cancer | Phase 2 | Completed | Shandong Simcere-Medgenn Bio-pharmaceutical Co., Ltd | 138 | 2009-05-01 | 2014-09-03 |
| Adjuvant Chemotherapy for Elderly Non Frail Patients With an Increased Risk for Relapse of a Primary Carcinoma of the Breast Epirubicin, Cyclophosphamide, Cyclophosphamide, Methotrexate, 5 FU, Capecitabine, Nab-Paclitaxel - Breast Cancer | Phase 2 / Phase 3 | Completed | GBG Forschungs GmbH | 400 | 2009-03-01 | 2016-02-10 |
| A Phase I/II Study of Carboplatin and Etoposide With or Without Obatoclax in Extensive-stage Small Cell Lung Cancer (ES-SCLC) Obatoclax, Carboplatin/etoposide - Extensive-stage Small Cell Lung Cancer | Phase 1 / Phase 2 | Completed | Gemin X | 218 | 2008-05-01 | 2016-07-21 |
Small Cell Lung Carcinoma (6) · Breast Neoplasms (3) · Carcinoma, Neuroendocrine (2) · Lung Neoplasms (1) · Triple Negative Breast Neoplasms (1)
Beijing Tiantan Hospital (1) · European Organisation for Research and Treatment of Cancer - EORTC (1) · GBG Forschungs GmbH (1) · Gemin X (1) · Gustave Roussy, Cancer Campus, Grand Paris (1) · Haihe Biopharma Co., Ltd. (1) · Henan Cancer Hospital (1) · Peking University (1) · Phanes Therapeutics (1) · Shandong Simcere-Medgenn Bio-pharmaceutical Co., Ltd (1) · Shanghai Chest Hospital (1) · TTY Biopharm (1) · The First Affiliated Hospital with Nanjing Medical University (1)
China (7) · France (2) · Germany (2) · Poland (2) · United Kingdom (2) · United States (2) · Belgium (1) · Bulgaria (1) · Canada (1) · Czechia (1) · Hungary (1) · India (1) · Italy (1) · Jordan (1) · Portugal (1)
Christelle Dufour, MD (1) · Guangyuan Hu, Doctor (1) · Gunter von Minckwitz, Prof. (1) · Hans Wildiers, MD, PhD (1) · Jean Viallet, MD (1) · Lin Shen (1) · Ming-Feng Hou, MD (1) · Qimig Wang, Doctor (1) · Shun Lu, Dr. (1) · Tao Jiang, MD, PhD (1) · Xiaoan Liu, Professor (1)
2008 (1)