3 completed, 2 active not recruiting, 1 available, 1 terminated. 3 Phase 2, 2 Phase 1, 1 Not applicable, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Active not recruiting 1, Completed 1, Terminated 1 |
| Phase 1 | 2 | Completed 1, Withdrawn 1 |
| Not applicable | 1 | Completed 1 |
| Phase 3 | 1 | Active not recruiting 1 |
Follow Dichloroacetate (DCA): new trials by email Literature Review of Dichloroacetate (DCA) trials Research Report on Dichloroacetate (DCA)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Trial of Dichloroacetate (DCA) in Glioblastoma Multiforme (GBM) Dichloroacetate (DCA), Genotype - Glioblastoma Multiforme | Phase 2 | Active not recruiting | University of Florida | 40 | 2022-07-01 | 2026-06-26 |
| Trial of Dichloroacetate in Pyruvate Dehydrogenase Complex Deficiency: Dichloroacetate (DCA), Placebo, Genotype - Pyruvate Dehydrogenase Complex Deficiency | Phase 3 | Active not recruiting | Saol Therapeutics Inc | 34 | 2020-07-14 | 2025-05-04 |
| A Pilot Study of Rapid Haplotyping Procedure for Personalized Dosing of Dichloroacetate (DCA) in Healthy Volunteers Dichloroacetate (DCA), GSTZ1 haplotyping - Healthy | Phase 1 | Completed | University of Florida | 45 | 2016-03-01 | 2018-12-31 |
| Dichloroacetate (DCA) in Patients With Previously Treated Metastatic Breast or Non-Small Cell Lung Cancer (NSCL) Dichloroacetate (DCA) - Metastatic Breast Cancer, Lung Cancer | Phase 2 | Terminated | Jonsson Comprehensive Cancer Center | 7 | 2009-12-01 | 2016-02-12 |
| Pharmacotoxicology of Trichloroethylene Metabolites Dichloroacetate (DCA), Genetic Marker on Chromosome 14q24.3 - Congenital Lactic Acidosis | Not applicable | Completed | University of Florida | 21 | 2009-08-01 | 2015-06-04 |
| Combining Radiotherapy and Temozolomide With Dichloroacetate in Patients With Newly Diagnosed Glioblastoma Dichloroacetate (DCA) - Glioblastoma | Phase 1 | Withdrawn | AHS Cancer Control Alberta | 2008-07-01 | 2016-02-22 | |
| The Safety and Efficacy of DCA for the Treatment of Brain Cancer Dichloroacetate (DCA) - Malignant Gliomas, Glioblastoma Multiforme | Phase 2 | Completed | University of Alberta | 40 | 2007-10-01 | 2014-10-13 |
| Expanded Access Treatment Protocol With DCA for Patients With PDCD Dichloroacetate (DCA) - Pyruvate Dehydrogenase Complex Deficiency | Available | Saol Therapeutics Inc | 2025-05-08 |
Glioblastoma (3) · Pyruvate Dehydrogenase Complex Deficiency Disease (2) · Breast Neoplasms (1) · Glioma (1) · Lung Neoplasms (1)
University of Florida (3) · Saol Therapeutics Inc (2) · AHS Cancer Control Alberta (1) · Jonsson Comprehensive Cancer Center (1) · University of Alberta (1)
United States (5) · Canada (1)
Peter W Stacpoole, PhD, MD (2) · Bassam Abdulkarim, MD, FRCPC (1) · Connor Maguire MD, investigator (1) · Edward Garon, MD (1) · Evangelos D Michelakis, MD co-PI (1) · Kenneth Petruk, MD co-PI (1) · Kiki Diorgu, M.D. (1) · Linda Webster, NP manager (1) · Peter Stacpoole, PhD, MD (1) · Richard Neibeger, MD (1)