11 completed. 8 Phase 1, 2 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 8 | Completed 8 |
| Phase 3 | 2 | Completed 2 |
| Phase 2 | 1 | Completed 1 |
Follow DBPR108: new trials by email Literature Review of DBPR108 trials Research Report on DBPR108
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate the Effect of Different Meal Types on the Pharmacokinetics of DBPR108 in Healthy Subjects DBPR108 tablets - Healthy Subjects | Phase 1 | Completed | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 21 | 2022-05-29 | 2023-04-12 |
| A Single-dose and Multiple-dose Study to Evaluate the Pharmacokinetics and Pharmacodynamics of DBPR108 Tablets in Type 2 Diabetes Mellitus Patients DBPR108 tablets - Type 2 Diabetes Mellitus | Phase 1 | Completed | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 30 | 2021-12-30 | 2022-04-05 |
| A Study to Evaluate the Drug-drug Interactions (DDIs) of DBPR108 With Warfarin Sodium, Digoxin, Probenecid in Healthy Subjects Warfarin sodium tablets, Digoxin tablet, Probenecid tablets - Healthy Subjects | Phase 1 | Completed | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 28 | 2021-10-20 | 2022-03-10 |
| A Study to Evaluate the Pharmacokinetics and Safety of DBPR108 in Subjects With Renal Impairment DBPR108 tablets - Renal Impairment | Phase 1 | Completed | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 40 | 2021-06-15 | 2022-05-10 |
| A Study to Evaluate the Pharmacokinetics and Safety of DBPR108 in Subjects With Hepatic Impairment DBPR108 tablets - Hepatic Impairment | Phase 1 | Completed | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 24 | 2021-06-09 | 2023-04-12 |
| A Study to Evaluate the DDI of DBPR108 With Metformin,Glibenclamide,Valsartan, or Simvastatin in Healthy Subjects DBPR108 tablets, Metformin hydrochloride tablets, Glibenclamide tablets - Healthy Subjects | Phase 1 | Completed | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 56 | 2021-05-26 | 2021-07-20 |
| A Study of DBPR108 and Metformin Hydrochloride Combination Therapy in Patients With T2DM DBPR108, metformin hydrochloride, placepo - Type 2 Diabetes Mellitus | Phase 3 | Completed | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 214 | 2020-01-14 | 2021-06-28 |
| A Study to Evaluate the Efficacy and Safety of DBPR108 100 mg in Type 2 Diabetes Mellitus Patients DBPR108; Placebo matching sitagliptin, Placebo matching DBPR108; Sitagliptin; DBPR108, Placebo matching DBPR108; Placebo matching sitagliptin; DBPR108 - Type 2 Diabetes Mellitus | Phase 3 | Completed | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 766 | 2020-01-02 | 2022-08-17 |
| DBPR108 Tablets in Type 2 Diabetes Mellitus Patients DBPR108 tablet(50mg), Placebo matching DBPR108 tablet(100mg), DBPR108 tablet(100mg), Placebo matching DBPR108 tablet(50mg), Placebo matching DBPR108 tablet(100mg), DBPR108 tablet(100mg), Placebo matching DBPR108 tablet(50mg) - Type 2 Diabetes Mellitus | Phase 2 | Completed | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 276 | 2017-10-17 | 2019-10-15 |
| A Multiple Ascending Dose Phase I Study of DBPR108 in Healthy Male Subjects DBPR108, matching placebo - Diabetes Mellitus, Type 2 | Phase 1 | Completed | National Health Research Institutes, Taiwan | 32 | 2014-06-01 | 2016-03-28 |
| A Single-dose Phase 1 Study of DBPR108 in Healthy Male Subjects DBPR108, matching placebo - Diabetes Mellitus, Type 2 | Phase 1 | Completed | National Health Research Institutes, Taiwan | 32 | 2012-07-01 | 2014-08-28 |
Diabetes Mellitus, Type 2 (6) · Diabetes Mellitus (2) · Renal Insufficiency (1)
CSPC ZhongQi Pharmaceutical Technology Co., Ltd. (9) · National Health Research Institutes, Taiwan (2)
China (9) · Taiwan (2)
Kun Lou (2) · Shan NA Jing, PhD (1) · Yang Lin, PhD (1)