6 terminated. 6 Phase 2, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Terminated 6 |
| Phase 1 | 3 | Terminated 3 |
Follow dactolisib: new trials by email Literature Review of dactolisib trials Research Report on dactolisib
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 2 Study to Determine if RTB101 Reduces the Severity of COVID-19 in Older Adults Residing in Nursing Homes RTB101, Placebo - COVID19 | Phase 2 | Terminated | Restorbio Inc. | 36 | 2020-07-11 | 2021-02-10 |
| Study of BEZ235 as Monotherapy in Patients With Transitional Cell Carcinoma After Failure of Platinum Based Chemotherapy BEZ235 - Carcinoma Transitional Cell | Phase 2 | Terminated | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | 22 | 2013-02-01 | 2019-04-10 |
| A Multicenter Phase I/II Trial of Abiraterone Acetate + BEZ235 in Metastatic, Castration-Resistant Prostate Cancer BEZ235, Prednisone, Abiraterone acetate - Castrate-resistant Prostate Cancer | Phase 1 / Phase 2 | Terminated | Charles Ryan | 6 | 2013-01-31 | 2018-03-27 |
| Efficacy and Safety of BEZ235 Compared to Everolimus in Patients With Advanced Pancreatic Neuroendocrine Tumors BEZ235, Everolimus - Pancreatic Neuroendocrine Tumors (pNET) | Phase 2 | Terminated | Novartis Pharmaceuticals | 62 | 2012-10-01 | 2016-04-07 |
| Phase Ib/II Trial of BEZ235 With Paclitaxel in Patients With HER2 Negative, Locally Advanced or Metastatic Breast Cancer BEZ235, Paclitaxel - Inoperable Locally Advanced Breast Cancer, Metastatic Breast Cancer (MBC) | Phase 1 / Phase 2 | Terminated | Novartis Pharmaceuticals | 18 | 2012-01-30 | 2020-12-08 |
| BEZ235 in Patients With Advanced Renal Cell Carcinoma (RCC) BEZ235 - Renal Cancer | Phase 1 / Phase 2 | Terminated | Memorial Sloan Kettering Cancer Center | 10 | 2011-10-01 | 2016-02-29 |
Breast Neoplasms (1) · COVID-19 (1) · Carcinoma, Renal Cell (1) · Carcinoma, Transitional Cell (1) · Hereditary Sensory and Autonomic Neuropathies (1) · Kidney Neoplasms (1) · Neoplasm Metastasis (1) · Neuroectodermal Tumors, Primitive (1) · Neuroendocrine Tumors (1) · Virus Diseases (1)
Novartis Pharmaceuticals (2) · Charles Ryan (1) · Cliniques universitaires Saint-Luc- Université Catholique de Louvain (1) · Memorial Sloan Kettering Cancer Center (1) · Restorbio Inc. (1)
United States (4) · France (2) · Spain (2) · Belgium (1) · Italy (1) · Luxembourg (1) · Netherlands (1) · Russia (1) · Switzerland (1) · United Kingdom (1)
Ana Molina, MD (1) · Charles Ryan, MD (1) · Jean-Pascal Machiels, MD, PhD (1)