8 completed. 8 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Completed 8 |
| Phase 1 | 1 | Completed 1 |
Follow Cystectomy: new trials by email Literature Review of Cystectomy trials Research Report on Cystectomy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pembrolizumab and Combination Chemotherapy Before Surgery for the Treatment of Muscle-Invasive Bladder Cancer Cisplatin, Doxorubicin, Methotrexate - Stage II Bladder Cancer AJCC v8, Stage IIIA Bladder Cancer AJCC v8 | Phase 2 | Completed | University of Washington | 17 | 2020-11-24 | 2025-09-18 |
| Avelumab as Neoadjuvant Therapy in Subjects With Urothelial Muscle Invasive Bladder Cancers (AURA Trial) Avelumab, cystectomy, CG - Non-metastatic Muscle Invasive Bladder Cancer | Phase 2 | Completed | Jules Bordet Institute | 137 | 2018-06-01 | 2025-02-26 |
| Sirolimus, Cisplatin, and Gemcitabine Hydrochloride in Treating Patients With Bladder Cancer Cisplatin, Gemcitabine Hydrochloride, Sirolimus - Recurrent Bladder Carcinoma, Stage II Bladder Cancer | Phase 1 / Phase 2 | Completed | University of Washington | 21 | 2013-10-01 | 2017-10-20 |
| Chemotherapy and Radiation Therapy in Treating Patients With Stage II or Stage III Bladder Cancer That Was Removed by Surgery induction cisplatin, induction 5-fluorouracil, induction gemcitabine - Bladder Cancer | Phase 2 | Completed | Radiation Therapy Oncology Group | 70 | 2008-12-01 | 2022-06-15 |
| Neoadjuvant ABI-007, Carboplatin and Gemcitabine in Locally Advanced Bladder Cancer ABI-007, Carboplatin, Gemcitabine - Bladder Cancer | Phase 2 | Completed | University of Michigan Rogel Cancer Center | 29 | 2007-12-01 | 2015-11-30 |
| Erlotinib Before and After Surgery in Treating Patients With Muscle-Invasive Bladder Cancer Erlotinib, Radical Cystectomy - Bladder Cancer | Phase 2 | Completed | UNC Lineberger Comprehensive Cancer Center | 27 | 2006-05-01 | 2017-07-19 |
| Neoadjuvant Chemo (Gemcitabine and Cisplatin) With Radical Cystectomy or Radiotherapy in Patients With Bladder Cancer gemcitabine, cisplatin, radical cystectomy - Bladder Cancer | Phase 2 | Completed | Eli Lilly and Company | 2 | 2003-11-01 | 2007-06-25 |
| Combination Chemotherapy and Radiation Therapy With/Without Surgery In Patients With Stage II/III Bladder Cancer cisplatin, fluorouracil, paclitaxel - Bladder Cancer | Phase 2 | Completed | Radiation Therapy Oncology Group | 97 | 2002-12-01 | 2018-06-15 |
Radiation Therapy Oncology Group (2) · University of Washington (2) · Eli Lilly and Company (1) · Jules Bordet Institute (1) · UNC Lineberger Comprehensive Cancer Center (1) · University of Michigan Rogel Cancer Center (1)
United States (6) · Belgium (1) · Canada (1) · France (1) · Poland (1)
Anthony L. Zietman, MD (1) · Cheryl T. Lee, MD (1) · Chin-Lee Wu, MD, PhD (1) · David C Smith, MD (1) · John J. Coen, MD (1) · Petros Grivas (1) · Philip J. Saylor, MD (1) · Raj S. Pruthi, MD (1) · Robert Dreicer, MD, FACP (1) · Robert Montgomery (1) · Robert Uzzo, MD (1)
PMID 20089114, PMID 21205754, PMID 23706253, PMID 23823157, PMID 25366678, PMID 34856936, PMID 40413024
P30CA015704 (1), P30CA016086 (1)