78 completed, 13 unknown, 10 terminated, 7 recruiting. 72 Phase 2, 25 Phase 1, 12 Phase 3, 8 Phase 4, 7 Not applicable.
Follow Cyclosporin A: new trials by email Literature Review of Cyclosporin A trials Research Report on Cyclosporin A
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ruxolitinib Based GVHD Prophylaxis Regimen Before, During, and After Hematopoietic Cell Transplantation in Older Adult Patients With Acquired Aplastic Anemia Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Aplastic Anemia | Phase 2 | Active not recruiting | Fred Hutchinson Cancer Center | 1 | 2025-09-25 | 2026-05-22 |
| Efficacy and Safety of rhTPO in Combination With Cyclosporine Versus Cyclosporine Alone in the Treatment of TD-NSAA rhTPO, Cyclosporin A - Aplastic Anemia, Transfusion-dependent Anemia | Phase 4 | Unknown | Peking Union Medical College Hospital | 54 | 2024-07-30 | 2024-07-29 |
| Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases Biospecimen Collection, Bone Marrow Aspirate, Cyclophosphamide - Acute Leukemia of Ambiguous Lineage, Acute Lymphoblastic Leukemia | Phase 2 | Recruiting | Fred Hutchinson Cancer Center | 54 | 2024-07-23 | 2026-10-26 |
| Breast/Cyclosporin A/TNBC (Triple Negative Breast Cancer) Cyclosporin A - Triple Negative Breast Cancer, DNA Damage Repair Deficiency | Early Phase 1 | Withdrawn | Virginia G. Kaklamani | 2024-07-01 | 2025-07-16 | |
| Outcomes With Treatment and Withdraw of Secukinumab in Patients With Plaque Psoriasis secukinumab, Methotrexate, Cyclosporin A - Plaque Psoriasis | Phase 4 | Not yet recruiting | Singapore General Hospital | 40 | 2024-01-01 | 2022-11-25 |
| Optimization of Cyclosporin in Atopic Dermatitis Through Multiomic Predictive Models of Treatment Response Cyclosporin A, Follow-up of Cyclospoin treatment already started - Atopic Dermatitis | Phase 4 | Unknown | Instituto de Investigación Hospital Universitario La Paz | 100 | 2022-10-10 | 2023-04-28 |
| Outcomes of Patients After Allo-HSCT With Decitabine and NAC decitabine, Acetylcysteine, Semustine - Engraft Failure, Relapse | Phase 3 | Unknown | The First Affiliated Hospital of Soochow University | 100 | 2021-07-01 | 2021-06-30 |
| Mycophenolate Mofetil Versus Cyclosporin A in the Treatment of Primary Biliary Cholangitis-autoimmune Hepatitis Overlap Syndrome Due to Nonresponse to Standard Therapy Cyclosporin A, Mycophenolate Mofetil - Hepatitis, Autoimmune, Primary Biliary Cholangitis | Phase 4 | Unknown | West China Hospital | 89 | 2021-06-16 | 2021-06-22 |
| Comparing ATG or Post-Transplant Cyclophosphamide to Calcineurin Inhibitor-Methotrexate as GVHD Prophylaxis After Myeloablative Unrelated Donor Peripheral Blood Stem Cell Transplantation Anti-Thymocyte Globulin, Busulfan, Cyclophosphamide - Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Phase 2 | Withdrawn | Fred Hutchinson Cancer Center | 2021-06-01 | 2021-06-30 | |
| Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies Allogeneic Hematopoietic Stem Cell Transplantation, Cyclophosphamide, Cyclosporine - Acute Leukemia, Acute Lymphoblastic Leukemia | Phase 2 | Recruiting | Fred Hutchinson Cancer Center | 60 | 2021-01-25 | 2026-05-29 |
| Outcomes With Treatment and Withdraw of Ixekizumab in Patients With Plaque Psoriasis Ixekizumab, Methotrexate, Cyclosporin A - Plaque Psoriasis | Phase 4 | Recruiting | Singapore General Hospital | 40 | 2020-12-10 | 2022-11-25 |
| CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemia Cladribine, Cyclophosphamide, Cyclosporine - Recurrent Acute Myeloid Leukemia, Recurrent Chronic Myelomonocytic Leukemia | Phase 1 | Recruiting | Fred Hutchinson Cancer Center | 120 | 2020-12-03 | 2026-09-17 |
| A Single-arm Trial of Prophylactic Tocilizumab for Acute GVHD Prevention After Haploidentical HSCT. Cytarabine, Busulfan, Cyclophosphamide - Leukemia, Graft-versus-host-disease | Phase 2 | Unknown | Yi Luo | 46 | 2020-12-03 | 2023-02-21 |
| Cyclosporine A Plus Low-steroid Treatment in COVID-19 Pneumonia Cyclosporin A - COVID 19 Pneumonia | Phase 1 / Phase 2 | Unknown | Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado | 200 | 2020-09-01 | 2020-09-07 |
| A Study Comparing Haploidentical Hematopoietic Stem Cell Transplantations (HSCTs) From Young Non-first-degree and Older First-degree Donors in Hematological Malignancies Cytarabine, Busulfan, Cyclophosphamide - Leukemia, MDS | Phase 3 | Active not recruiting | First Affiliated Hospital of Zhejiang University | 232 | 2020-09-01 | 2026-04-09 |
| Donor Stem Cell Transplant After Chemotherapy for the Treatment of Recurrent or Refractory High-Risk Solid Tumors in Pediatric and Adolescent-Young Adults Allogeneic Hematopoietic Stem Cell Transplantation, Cyclosporine, Etoposide - Desmoplastic Small Round Cell Tumor, Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Phase 2 | Terminated | M.D. Anderson Cancer Center | 1 | 2020-08-19 | 2025-06-29 |
| Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant Patients With Acute Leukemia or Myelodysplastic Syndrome (MDS) Total-Body Irradiation, Thiotepa, Fludarabine - Acute Leukemia, Acute Lymphoblastic Leukemia | Phase 2 | Recruiting | Fred Hutchinson Cancer Center | 120 | 2019-11-19 | 2026-10-20 |
| 211^At-BC8-B10 Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, or Mixed-Phenotype Acute Leukemia Cyclosporine, Fludarabine Phosphate, Mycophenolate Mofetil - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Phase 1 / Phase 2 | Recruiting | Fred Hutchinson Cancer Center | 75 | 2017-10-24 | 2026-06-22 |
| Comparison of Triple GVHD Prophylaxis Regimens for Nonmyeloablative or Reduced Intensity Conditioning Unrelated Mobilized Blood Cell Transplantation Allogeneic Hematopoietic Stem Cell Transplantation, Cyclophosphamide, Cyclosporine - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | Phase 2 | Terminated | Fred Hutchinson Cancer Center | 150 | 2017-09-11 | 2026-05-14 |
| Alitretinoin vs Cyclosporine in Severe Recurrent Vesicular Hand Eczema Alitretinoin, cyclosporin A - Hand Eczema | Phase 3 | Unknown | University Medical Center Groningen | 76 | 2017-05-29 | 2019-02-26 |
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PMID 32499241, PMID 12867568, PMID 15494274, PMID 16192477, PMID 17192769, PMID 18565970, PMID 18698002, PMID 19218475, PMID 19423725, PMID 19786617, PMID 19900571, PMID 20421389, PMID 20528878, PMID 20661232, PMID 21249305, PMID 21508120, PMID 21508413, PMID 21606164, PMID 21752960, PMID 22300431, PMID 22773122, PMID 23454241, PMID 23620378, PMID 23698397, PMID 24307695, PMID 24607552, PMID 24819773, PMID 24831918, PMID 25720466, PMID 26146806, PMID 26321103, PMID 26764356, PMID 26888217, PMID 27433815, PMID 27449641, PMID 29161116, PMID 29296873, PMID 29772254, PMID 29997136, PMID 30097460, PMID 30157400, PMID 30179381, PMID 30335787, PMID 30454872, PMID 30630975, PMID 30880061, PMID 30951840, PMID 31248843, PMID 31582553, PMID 31637757
P30CA015704 (39), P01CA018029 (13), P01CA078902 (8), P01CA044991 (4), P30CA016672 (4), P01HL036444 (3), P30CA043703 (2), RC2HL101844 (2), K23CA190849 (1), K23HL084054 (1), P01CA049605 (1), P30CA046592 (1), P30CA046934 (1), R21CA155911 (1), R24HL074445 (1)