18 completed, 1 active not recruiting. 11 Phase 1, 5 Phase 2, 4 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 11 | Completed 11 |
| Phase 2 | 5 | Completed 4, Active not recruiting 1 |
| Phase 3 | 4 | Completed 3, Active not recruiting 1 |
Follow CTP-543: new trials by email Literature Review of CTP-543 trials Research Report on CTP-543
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study to Evaluate Multiple Doses of Fluconazole, a CYP3A4 and CYP2C9 Inhibitor, on the Pharmacokinetics of CTP-543 in Healthy Subjects CTP-543, Fluconazole - Health Volunteers | Phase 1 | Completed | Concert Pharmaceuticals | 18 | 2022-07-11 | 2022-08-30 |
| Study To Evaluate The Effect Of Multiple Doses of CTP-543 On The Pharmacokinetics Of Single Doses of Midazolam In Healthy Subjects Midazolam, CTP-543 - Health Volunteers | Phase 1 | Completed | Concert Pharmaceuticals | 20 | 2022-06-21 | 2022-07-20 |
| Study of the Effect of Food on the Bioavailability of the To-Be-Marketed Formulation of CTP-543 in Healthy Volunteers CTP-543 - Health Volunteers | Phase 1 | Completed | Concert Pharmaceuticals | 16 | 2022-06-14 | 2022-07-20 |
| Study to Assess the Effect of Renal Impairment on the Pharmacokinetics of CTP-543 CTP-543 - Renal Impairment | Phase 1 | Completed | Concert Pharmaceuticals | 16 | 2022-06-06 | 2022-11-29 |
| Study to Assess the Effect of Hepatic Impairment on the Pharmacokinetics of CTP-543 CTP-543 - Hepatic Impairment | Phase 1 | Completed | Concert Pharmaceuticals | 21 | 2022-06-01 | 2022-11-29 |
| A Randomized Study to Evaluate the Effects of CTP-543 on the QT/QTc Intervals in Health Volunteers CTP-543, Moxifloxacin, Placebo - Healthy Volunteers | Phase 1 | Completed | Concert Pharmaceuticals | 48 | 2022-01-04 | 2022-03-04 |
| European Extension Study to Evaluate Safety and Efficacy of CTP-543 in Adults With Alopecia Areata CTP-543 - Alopecia Areata | Phase 3 | Completed | Sun Pharmaceutical Industries, Inc. | 407 | 2021-10-19 | 2025-11-21 |
| Study to Evaluate the Efficacy and Safety of CTP-543 in Adults With Moderate to Severe Alopecia Areata (THRIVE-AA2) CTP-543 matching placebo, CTP-543 - Alopecia Areata | Phase 3 | Completed | Concert Pharmaceuticals | 517 | 2021-06-10 | 2023-07-03 |
| Drug-drug Interaction Study of CTP-543 and Rifampin in Healthy Adult Subjects CTP-543 - Healthy Volunteers | Phase 1 | Completed | Concert Pharmaceuticals | 22 | 2021-05-19 | 2021-07-20 |
| Drug-drug Interaction Study of CTP-543 and Itraconazole in Healthy Adult Subjects CTP-543 - Healthy Volunteers | Phase 1 | Completed | Concert Pharmaceuticals | 22 | 2021-03-02 | 2021-04-08 |
| A Study to Evaluate the Durability of Response of CTP-543 in Adult Patients With Moderate to Severe Alopecia Areata CTP-543, Placebo - Alopecia Areata | Phase 2 | Completed | Concert Pharmaceuticals | 317 | 2021-02-26 | 2024-10-09 |
| Study to Evaluate the Efficacy and Safety of CTP-543 in Adults With Moderate to Severe Alopecia Areata (THRIVE-AA1) CTP-543 matching placebo, CTP-543 - Alopecia Areata | Phase 3 | Completed | Concert Pharmaceuticals | 706 | 2020-11-23 | 2023-05-03 |
| Drug-drug Interaction Study of CTP-543 and Oral Contraceptives in Healthy Female Subjects CTP-543, Combined oral contraceptive containing Ethinyl estradiol (EE) and Levonorgestrel (LNG) - Healthy Volunteers | Phase 1 | Completed | Concert Pharmaceuticals | 21 | 2020-06-09 | 2020-07-16 |
| Efficacy and Tolerability Study of Two Dosing Regimens of CTP-543 in Adults With Alopecia Areata CTP-543, CTP-543 Matching Placebo - Alopecia Areata | Phase 2 | Completed | Concert Pharmaceuticals | 66 | 2019-05-24 | 2023-04-05 |
| Extension Study to Evaluate Safety and Efficacy of CTP-543 in Adults With Alopecia Areata CTP-543 - Alopecia Areata | Phase 2 / Phase 3 | Active not recruiting | Sun Pharmaceutical Industries, Inc. | 1000 | 2019-04-04 | 2025-10-22 |
| Food Effect Study of CTP-543 in Healthy Volunteers CTP-543 - Healthy | Phase 1 | Completed | Concert Pharmaceuticals | 14 | 2019-03-25 | 2019-06-13 |
| Efficacy and Tolerability Study of Two Dose Regimens of CTP-543 in Adults With Alopecia Areata CTP-543, CTP-543 Matching Placebo - Alopecia Areata | Phase 2 | Completed | Concert Pharmaceuticals | 57 | 2019-03-21 | 2022-12-09 |
| Study to Evaluate the Safety and Efficacy of CTP-543 in Adults With Moderate to Severe Alopecia Areata CTP-543, CTP-543 matching placebo - Alopecia Areata | Phase 2 | Completed | Concert Pharmaceuticals | 149 | 2017-08-09 | 2022-07-19 |
| Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of CTP-543 in Healthy Subjects CTP-543, Placebo for CTP-543 - Healthy | Phase 1 | Completed | Concert Pharmaceuticals | 77 | 2016-05-01 | 2017-03-13 |
Alopecia Areata (8) · Alopecia (2) · Hair Diseases (2) · Renal Insufficiency (1)
Concert Pharmaceuticals (17) · Sun Pharmaceutical Industries, Inc. (2)
United States (17) · Canada (4) · France (3) · Poland (3) · Spain (3) · Germany (2) · Hungary (2) · Australia (1)
Colleen E Hamilton, MS (1) · Colleen E. Hamilton (1) · Colleen Hamilton (1)