29 completed, 4 unknown, 3 terminated, 1 withdrawn. 12 Phase 4, 8 Phase 3, 5 Phase 2, 2 Not applicable, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 12 | Completed 7, Unknown 3, Terminated 2 |
| Phase 3 | 8 | Completed 7, Withdrawn 1 |
| Phase 2 | 5 | Completed 4, Terminated 1 |
| Not applicable | 2 | Completed 2 |
| Phase 1 | 2 | Completed 2 |
Follow Corifollitropin Alfa: new trials by email Literature Review of Corifollitropin Alfa trials Research Report on Corifollitropin Alfa
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Continuous Double Ovarian Stimulation. Corifollitropin Alfa, Follitropin Alfa, Follitropin Alfa Biosimilar - Fertility Issues | Phase 4 | Completed | Instituto Bernabeu | 30 | 2022-11-17 | 2025-05-18 |
| Reduction of Progesterone Elevation at Trigger in POR After Long Acting COS Compared With Daily COS: a Prospective Randomized Trial Corifollitropin alfa, Follitropin Beta - Infertility | Phase 4 | Completed | IRCCS San Raffaele | 110 | 2022-02-22 | 2024-05-16 |
| The Relationship Between Serum AMH Dynamics and Early or Normal Ovarian Response to Corifollitropin Alfa Corifollitropin alfa - Infertility, Female | Unknown | Azienda Ospedaliero-Universitaria di Modena | 80 | 2020-08-01 | 2023-02-08 | |
| An Observational Study of Follitropin Alpha Biosimilar: the Real-world Data Follitropin Alfa, Follicle Stimulating Hormone/Luteinizing Hormone - Reproductive Issues, Reproductive Disorder | Completed | IVFarma LLC | 5484 | 2020-01-12 | 2021-10-22 | |
| Corifollitropin Alpha and Ovarian Response Corifollitropin Alfa, Menotropins - Infertility, Female | Not applicable | Completed | Hospital de Clinicas de Porto Alegre | 300 | 2018-06-15 | 2020-06-04 |
| Optimisation of Follicular Recruitment in IVM Cycles blood sampling, transvaginal ultrasound scanning, oocyte retrieval for IVM - Infertility, Female, Polycystic Ovary Syndrome | Phase 3 | Completed | Universitair Ziekenhuis Brussel | 145 | 2017-11-01 | 2023-04-07 |
| Prospective Randomized Trial Comparing Corifollitropin-alfa Late Start vs. Corifollitropin-alfa Standard Start in Expected Poor, Normal and High-responders Undergoing IVF Corifollitropin Alfa - Fertility Disorders | Not applicable | Completed | University of Turin, Italy | 113 | 2017-04-01 | 2019-01-25 |
| Efficacy and Safety of Corifollitropin Alfa (MK-8962) in Combination With Human Chorionic Gonadotropin (hCG) in Adolescent Males With Hypogonadotropic Hypogonadism (HH) (MK-8962-043) Corifollitropin alfa, hCG - Hypogonadotropic Hypogonadism | Phase 3 | Completed | Organon and Co | 17 | 2017-02-02 | 2024-05-23 |
| Corifollitropin Alfa Versus Follitropin Beta in High Responders Elonva, Puregon - Infertility | Phase 4 | Unknown | Eugonia | 62 | 2015-09-01 | 2015-06-22 |
| Efficacy of Corifollitropin Alfa Versus Follitropin Beta in Aged IVF (In-vitro Fertilization) Patients corifollitropin alfa, Follitropin Beta - Infertility | Phase 4 | Completed | Vietnam National University | 400 | 2015-06-01 | 2017-08-22 |
| Type of Gonadotropin and Embryo Kinetics of Development Corifollitropin alfa - Infertility | Phase 4 | Terminated | IVI Madrid | 201 | 2015-04-01 | 2022-08-11 |
| Corifollitropin Alfa on D5 Versus D7 After Contraceptive Pill Corifollitropin alfa - Oocyte Donation | Phase 4 | Completed | Fundacion Dexeus | 70 | 2015-02-01 | 2017-05-16 |
| Elonva in Combination With Hp-FSH Versus Elonva With Low Dose hCG low dose hCG, hp-FSH, Corifollitropin Alfa - Infertility | Phase 4 | Completed | AZ Jan Palfijn Gent | 107 | 2014-10-01 | 2021-02-03 |
| Use of Corifolitropin Alfa in Oocyte Donors Corifollitropin alfa, Recombinant FSH, HP-hMG - Female Reproductive Problem, Infertility | Phase 4 | Unknown | IVI Madrid | 300 | 2014-10-01 | 2015-07-17 |
| Corifollitropin Alfa Versus Daily rFSH in the Controlled Ovarian Stimulation of Poor Responders Corifollitropin alfa - Infertility | Phase 4 | Terminated | Vida Recoletas Sevilla | 26 | 2014-09-01 | 2016-01-18 |
| An Efficacy and Safety Study of Corifollitropin Alfa (MK-8962) in Contrast to Recombinant FSH for Use in Controlled Ovarian Stimulation of Indian Women (P07056, Also Known as MK-8962-029) MK-8962, recFSH, Ganirelix - Infertility | Phase 3 | Withdrawn | Organon and Co | 2014-03-01 | 2022-02-03 | |
| Corifollitropin Alfa Application in PCOS Patients Corifollitropin alfa - In Vitro Fertilization | Phase 4 | Unknown | Shin Kong Wu Ho-Su Memorial Hospital | 30 | 2014-01-01 | 2014-08-13 |
| Corifollitropin Alfa Followed by Menotropin for Poor Ovarian Responders Trial Corifollitropin alfa, recombinant FSH, Ganirelix - Infertility, Poor Ovarian Response | Phase 3 | Completed | Universitair Ziekenhuis Brussel | 150 | 2013-03-01 | 2016-06-23 |
| A Study of the Efficacy and Safety of Corifollitropin Alfa (MK-8962) in Combination With Human Chorionic Gonadotropin (hCG) in Adult Men With Hypogonadotropic Hypogonadism (HH) (P07937) Corifollitropin alfa, hCG - Hypogonadism, Hypogonadotropic Hypogonadism | Phase 3 | Completed | Organon and Co | 18 | 2013-02-11 | 2024-05-24 |
| Treatment of Poor Ovarian Responders With Corifollitropin Alfa Followed by hpHMG in a Short GnRH Agonist Protocol Triptorelin, Corifollitropin alfa, hpHMG - Infertility, Poor Ovarian Response | Phase 2 | Completed | Universitair Ziekenhuis Brussel | 51 | 2012-07-01 | 2013-05-09 |
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Infertility (20) · Congenital Abnormalities (5) · Infertility, Female (4) · Hypogonadism (2) · Polycystic Ovary Syndrome (2) · Genital Diseases, Female (1) · Helping Behavior (1) · Ovarian Hyperstimulation Syndrome (1)
Organon and Co (17) · Universitair Ziekenhuis Brussel (4) · IVI Madrid (2) · AZ Jan Palfijn Gent (1) · Aristotle University Of Thessaloniki (1) · Azienda Ospedaliero-Universitaria di Modena (1) · Eugonia (1) · Fundacion Dexeus (1) · Hospital de Clinicas de Porto Alegre (1) · IRCCS San Raffaele (1) · IVFarma LLC (1) · Instituto Bernabeu (1) · National and Kapodistrian University of Athens (1) · Shin Kong Wu Ho-Su Memorial Hospital (1) · University of Turin, Italy (1)
Belgium (5) · Italy (4) · Spain (4) · Greece (3) · Brazil (2) · Russia (2) · Vietnam (2) · Denmark (1) · Mexico (1) · South Africa (1) · Taiwan (1)
Nikolaos P Polyzos, MD PhD (2) · Antonio La Marca (1) · Antonio Requena, MD, PhD (1) · Dilorom Kamilova, PhD (1) · Efstratios M Kolibianakis, MD, MSc, PhD (1) · Enrico Papaleo, MD (1) · Jiann-Loung Hwang, MD (1) · Juan Carlos Castillo Farfan, MD, PhD (1) · Trifon G Lainas, PhD (1) · Wim Decleer, MD (1)
PMID 22587997, PMID 19684043, PMID 26991902, PMID 26950065, PMID 12748128, PMID 15155606, PMID 18684735, PMID 20149360, PMID 20843746, PMID 21622693, PMID 21828117, PMID 21892335, PMID 23352098, PMID 23758821, PMID 24161646, PMID 24813196, PMID 24903202, PMID 25444501, PMID 25492411, PMID 26187300, PMID 27090863, PMID 27619773, PMID 28270212, PMID 28508691, PMID 29040589, PMID 29963011, PMID 30895237, PMID 32185595, PMID 32338123, PMID 38983736
2004 (3), 2015 (1)