CIN-107: Clinical Trials

7 completed. 7 Phase 1.

By phase and status

Phase	Trials	Status
Phase 1	7	Completed 7

Follow CIN-107: new trials by email Literature Review of CIN-107 trials Research Report on CIN-107

Trials (filtered) newest first · largest first

All 7 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
A Study to Investigate the Pharmacokinetics of Baxdrostat When Given Alone and in Combination With Itraconazole in Healthy Participants Baxdrostat, Itraconazole - Healthy Participants	Phase 1	Completed	AstraZeneca	14	2024-04-16	2024-07-03
Baxdrostat Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study in a Japanese Population baxdrostat - Hypertension	Phase 1	Completed	AstraZeneca	41	2022-07-05	2023-08-14
Phase 1 Study to Determine the Metabolism and Clearance of Baxdrostat baxdrostat - Hypertension	Phase 1	Completed	AstraZeneca	8	2021-11-18	2023-08-15
Phase 1 PK Study to Evaluate the PK of CIN-107 in Subjects With Hepatic Impairment baxdrostat - Hypertension	Phase 1	Completed	AstraZeneca	20	2021-08-10	2023-08-14
Study to Evaluate the Pharmacokinetics of CIN-107 in Subjects With Varying Degrees of Renal Function CIN-107 - Hypertension	Phase 1	Completed	AstraZeneca	33	2021-01-12	2023-08-14
Study to Evaluate the Effect of CIN-107 on the Pharmacokinetics of the MATE Substrate, Metformin, in Healthy Subjects Metformin, CIN-107 - Hypertension	Phase 1	Completed	AstraZeneca	27	2020-10-28	2023-08-14
Study With CIN-107 Following Multiple Oral Ascending Doses in Healthy Subjects CIN-107, Matching Placebo - Hypertension	Phase 1	Completed	AstraZeneca	56	2019-12-19	2023-08-14

Conditions studied

Hypertension (6)

Sponsors

AstraZeneca (7)

Countries

United States (7)

Top investigators

Eric Lawitz, MD (1)  ·  Kimberly Cruz, MD (1)  ·  Leela Leela Vrishabhendra, MD, MD (1)  ·  Leela Vrishabhendra, MD (1)  ·  Nicholas Siebers, MD Siebers, MD (1)  ·  Peter J Winkle, MD (1)  ·  Thomas Marbury, MD (1)  ·  William B Smith,, MD (1)  ·  Zeid Kayali, MD (1)