75 completed, 14 terminated, 9 recruiting, 2 active not recruiting. 65 Phase 2, 24 Phase 1, 11 Phase 3, 6 Not applicable, 6 Phase 4.
Follow Ciclosporin: new trials by email Literature Review of Ciclosporin trials Research Report on Ciclosporin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study in Healthy Men to Find Out How Blocking Certain Transport Proteins Affects the Amount of BI 3000202 in the Blood BI 3000202, Ciclosporin, Itraconazole - Healthy | Phase 1 | Active not recruiting | Boehringer Ingelheim | 16 | 2026-09-01 | 2026-10-13 |
| A Study to Compare the Effectiveness and Safety of T1695 Versus Ciclosporin in Participants With Moderate to Severe Vernal Keratoconjunctivitis Slit Lamp Examination, Far Best Corrected Visual Acuity (BCVA), T1695 - Moderate to Severe Vernal Keratoconjunctivitis | Phase 2 | Recruiting | Laboratoires Thea | 120 | 2026-03-24 | 2026-04-22 |
| RCT of Tocilizumab for Anti-MDA5+DM Tocilizumab, Standard medical treatment - Dermatomyositis | Not applicable | Recruiting | Peking Union Medical College Hospital | 110 | 2025-11-01 | 2026-01-29 |
| Ruxolitinib Based GVHD Prophylaxis Regimen Before, During, and After Hematopoietic Cell Transplantation in Older Adult Patients With Acquired Aplastic Anemia Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Aplastic Anemia | Phase 2 | Active not recruiting | Fred Hutchinson Cancer Center | 1 | 2025-09-25 | 2026-05-22 |
| Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases Biospecimen Collection, Bone Marrow Aspirate, Cyclophosphamide - Acute Leukemia of Ambiguous Lineage, Acute Lymphoblastic Leukemia | Phase 2 | Recruiting | Fred Hutchinson Cancer Center | 54 | 2024-07-23 | 2026-07-22 |
| CsA+ATG+AVA vs. CsA+AVA for the Treatment of Newly-diagnosed SAA in the Elderly Ciclosporin, Avatrombopag, Anti-Human Thymocyte Immunoglobulin, Rabbit - Aplastic Anemia | Phase 4 | Completed | Peking Union Medical College Hospital | 86 | 2023-09-15 | 2025-04-30 |
| Efficacy and Safety of CsA+AVA in the Treatment of NSAA in the Elderly Ciclosporin, Avatrombopag - Aplastic Anemia | Phase 2 | Unknown | Peking Union Medical College Hospital | 30 | 2023-08-17 | 2023-12-08 |
| Romiplostim in Combination With CsA vs. CsA in the Treatment of Newly Diagnosed NSAA Romiplostim, Ciclosporin - Non Severe Aplastic Anemia | Phase 4 | Unknown | Peking Union Medical College Hospital | 44 | 2023-08-01 | 2023-08-24 |
| Efficacy and Safety in Transfusion Independent Non-severe Aplastic Anemia Luspatercept, Cyclosporine - Aplastic Anemia | Phase 2 | Completed | Bing Han | 58 | 2022-12-19 | 2025-09-16 |
| A Study in Healthy Adult Participants to Assess the Effects of Ciclosporin Administration on Rilematovir Rilematovir, Ciclosporin - Healthy | Phase 1 | Completed | Janssen Research & Development, LLC | 18 | 2021-12-10 | 2025-02-03 |
| Comparing ATG or Post-Transplant Cyclophosphamide to Calcineurin Inhibitor-Methotrexate as GVHD Prophylaxis After Myeloablative Unrelated Donor Peripheral Blood Stem Cell Transplantation Anti-Thymocyte Globulin, Busulfan, Cyclophosphamide - Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Phase 2 | Withdrawn | Fred Hutchinson Cancer Center | 2021-06-01 | 2021-06-30 | |
| Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies Allogeneic Hematopoietic Stem Cell Transplantation, Cyclophosphamide, Cyclosporine - Acute Leukemia, Acute Lymphoblastic Leukemia | Phase 2 | Recruiting | Fred Hutchinson Cancer Center | 60 | 2021-01-25 | 2026-05-29 |
| CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemia Cladribine, Cyclophosphamide, Cyclosporine - Recurrent Acute Myeloid Leukemia, Recurrent Chronic Myelomonocytic Leukemia | Phase 1 | Recruiting | Fred Hutchinson Cancer Center | 120 | 2020-12-03 | 2026-09-17 |
| Donor Stem Cell Transplant After Chemotherapy for the Treatment of Recurrent or Refractory High-Risk Solid Tumors in Pediatric and Adolescent-Young Adults Allogeneic Hematopoietic Stem Cell Transplantation, Cyclosporine, Etoposide - Desmoplastic Small Round Cell Tumor, Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Phase 2 | Terminated | M.D. Anderson Cancer Center | 1 | 2020-08-19 | 2025-06-29 |
| Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant Patients With Acute Leukemia or Myelodysplastic Syndrome (MDS) Total-Body Irradiation, Thiotepa, Fludarabine - Acute Leukemia, Acute Lymphoblastic Leukemia | Phase 2 | Recruiting | Fred Hutchinson Cancer Center | 120 | 2019-11-19 | 2026-10-20 |
| Spanish Academy of Dermatology and Venereology Registry of Atopic Dermatitis Therapy Ciclosporin - Dermatitis, Atopic | Recruiting | Fundación Academia Española de Dermatología | 2500 | 2019-01-01 | 2023-01-06 | |
| A Trial Investigating the Effect of Probenecid and Ciclosporin on the Concentrations of SNAC in Healthy Subjects Semaglutide, Probenecid, Ciclosporin - Diabetes, Diabetes Mellitus, Type 2 | Phase 1 | Completed | Novo Nordisk A/S | 21 | 2018-03-15 | 2019-06-19 |
| 211^At-BC8-B10 Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, or Mixed-Phenotype Acute Leukemia Cyclosporine, Fludarabine Phosphate, Mycophenolate Mofetil - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Phase 1 / Phase 2 | Recruiting | Fred Hutchinson Cancer Center | 75 | 2017-10-24 | 2026-06-22 |
| Comparison of Triple GVHD Prophylaxis Regimens for Nonmyeloablative or Reduced Intensity Conditioning Unrelated Mobilized Blood Cell Transplantation Allogeneic Hematopoietic Stem Cell Transplantation, Cyclophosphamide, Cyclosporine - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | Phase 2 | Terminated | Fred Hutchinson Cancer Center | 150 | 2017-09-11 | 2026-05-14 |
| Brentuximab Vedotin, Cyclosporine, and Verapamil Hydrochloride in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma Brentuximab Vedotin, Cyclosporine, Pharmacokinetic Study - Recurrent Hodgkin Lymphoma, Refractory Hodgkin Lymphoma | Phase 1 | Completed | City of Hope Medical Center | 29 | 2017-05-03 | 2024-02-22 |
Showing 20 of 104. Sign in to see all of them.
Leukemia, Myeloid, Acute (35) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (31) · Leukemia, Lymphocytic, Chronic, B-Cell (28) · Multiple Myeloma (24) · Hodgkin Disease (23) · Lymphoma, Non-Hodgkin (23) · Lymphoma, Mantle-Cell (20) · Lymphoma, Large B-Cell, Diffuse (19) · Waldenstrom Macroglobulinemia (18) · Congenital Abnormalities (17) · Leukemia, Myeloid, Chronic-Phase (17) · Lymphoma, B-Cell, Marginal Zone (17) · Lymphoma, Follicular (17) · Burkitt Lymphoma (16) · Leukemia, Myelomonocytic, Chronic (16)
Fred Hutchinson Cancer Center (52) · National Cancer Institute (NCI) (5) · Case Comprehensive Cancer Center (4) · London School of Hygiene and Tropical Medicine (4) · Peking Union Medical College Hospital (4) · Stanford University (3) · M.D. Anderson Cancer Center (2) · Novartis Pharmaceuticals (2) · Aurinia Pharmaceuticals Inc. (1) · Bing Han (1) · Boehringer Ingelheim (1) · Charite University, Berlin, Germany (1) · City of Hope Medical Center (1) · Eli Lilly and Company (1) · Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium (1)
United States (72) · Germany (12) · Italy (11) · China (5) · United Kingdom (5) · Ethiopia (4) · Denmark (3) · Canada (2) · France (2) · Spain (2) · Sweden (2) · Austria (1) · Belgium (1) · Brazil (1) · India (1)
Brenda Sandmaier (12) · David Maloney (6) · Marco Mielcarek (4) · Johnnie Orozco (3) · Ajay Gopal (2) · Ann Woolfrey (2) · Colleen Delaney (2) · Diana NJ Lockwood, MBChB (2) · Filippo Milano (2) · George Georges (2) · Hans-Peter Kiem (2) · Lauri Burroughs (2) · Masumi Ueda Oshima (2) · Robert Lowsky (2)
PMID 32499241, PMID 18698002, PMID 19786617, PMID 19900571, PMID 21508120, PMID 21508413, PMID 21606164, PMID 22720101, PMID 23594858, PMID 26270340, PMID 26764356, PMID 27979834, PMID 28967549, PMID 29296873, PMID 30335787, PMID 30454872, PMID 30630975, PMID 31248843, PMID 31582553, PMID 31637757, PMID 32067256, PMID 32603426, PMID 32706891, PMID 32710011, PMID 33242441, PMID 35445027, PMID 37100060, PMID 41043099, PMID 42057135
P30CA015704 (39), P01CA018029 (13), P01CA078902 (8), P01CA044991 (4), P01HL036444 (3), 2014 (2), P30CA043703 (2), RC2HL101844 (2), 2004 (1), 2009 (1), 2017 (1), 2025 (1), K23CA190849 (1), K23HL084054 (1), P01CA049605 (1)