4 completed, 1 not yet recruiting, 1 withdrawn. 2 Phase 1, 2 Phase 2, 1 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Completed 2 |
| Phase 2 | 2 | Completed 1, Withdrawn 1 |
| Not applicable | 1 | Not yet recruiting 1 |
| Phase 4 | 1 | Completed 1 |
Follow Chloroquine (CQ): new trials by email Literature Review of Chloroquine (CQ) trials Research Report on Chloroquine (CQ)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Tafenoquine Combinations for Improved Radical Cure Efficacy of Plasmodium Vivax Tafenoquine (TQ), Chloroquine (CQ), Dihydroartemisinin-piperaquine (DHA-PPQ) - Uncomplicated P. Vivax Mono-infection | Not applicable | Not yet recruiting | Walter Reed Army Institute of Research (WRAIR) | 300 | 2026-05-01 | 2026-04-16 |
| Chloroquine (CQ) and Azithromycin (AZ) Combination for Malaria Prophylaxis Chloroquine-Azithromycin (CQ/AZ), Chloroquine (CQ), atovaquone-proguanil (Malarone®) - Malaria | Phase 2 | Withdrawn | U.S. Army Medical Research and Development Command | 2018-09-17 | 2020-02-27 | |
| Sanaria PfSPZ Challenge With Pyrimethamine Chemoprophylaxis (PfSPZ-CVac Approach): Phase 1 Trial to Determine Safety and Protective Efficacy of Sanaria PfSPZ Challenge With Concurrent Pyrimethamine Treatment That Inhibits Development of Asexual B... Chloroquine (CQ), Pyrimethamine (PYR), Sanaria PfSPZ Challenge (NF54) - Malaria | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 57 | 2015-07-21 | 2017-07-02 |
| A Phase 1 Study To Estimate The Relative Bioavailability Of Co-Administered Formulations Of Azithromycin Microsphere And Chloroquine Test Formulation Compared With Co-Administered Immediate Release Individual Azithromycin And Chloroquine Tablets In Healthy Adult Subjects azithromycin (AZ) microsphere, test chloroquine (CQ) formulation, azithromycin (AZ) - Malaria Prophylaxis | Phase 1 | Completed | Pfizer | 40 | 2010-04-01 | 2010-08-25 |
| Prevention of Intrauterine Growth Retardation in Burkina Faso: the Malaria Component Multiple micronutrients supplements (MMS), Iron and folic acid (IFA), Chloroquine (CQ) - Malaria, Malaria in Pregnancy | Phase 4 | Completed | Institute of Tropical Medicine, Belgium | 1370 | 2003-06-01 | 2010-09-14 |
| Trial of Artesunate Combination Therapy in Pakistan artesunate (AS), sulphadoxine-pyrimethamine (SP), Chloroquine (CQ) - Uncomplicated Falciparum Malaria | Phase 2 | Completed | London School of Hygiene and Tropical Medicine | 588 | 2001-07-01 | 2009-08-14 |
Malaria (3) · Birth Weight (1) · Infections (1) · Malaria, Vivax (1)
Institute of Tropical Medicine, Belgium (1) · London School of Hygiene and Tropical Medicine (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Pfizer (1) · U.S. Army Medical Research and Development Command (1) · Walter Reed Army Institute of Research (WRAIR) (1)
United States (3) · Burkina Faso (1) · Pakistan (1) · Thailand (1)
Brian Vesely, PhD (1) · Jeffrey R Livezey, MD (1) · Marie Claire Henry, MD (1) · Mark W Rowland, PhD (1) · Sara A Healy, M.D. (1)
PMID 11832638, PMID 15838784, PMID 17213921, PMID 22303437, PMID 32938444, PMID 34194041, PMID 9455524