4 completed, 1 terminated. 5 Phase 1, 1 Phase 2.
By phase and status
Follow CC-223: new trials by email Literature Review of CC-223 trials Research Report on CC-223
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
Novel Combinations of CC-122, CC-223, CC-292, and Rituximab in Diffuse Large B-cell Lymphoma and Follicular Lymphoma CC-122, CC-223, Rituximab - Lymphoma, Large B-Cell, Diffuse | Phase 1 | Terminated | 174 | 2013-12-18 | 2024-01-18 |
CC-223 and Ketoconazole Drug-Drug Interaction Study CC-223, Ketoconazole - Healthy Volunteers | Phase 1 | Completed | 14 | 2013-07-01 | 2019-11-12 |
A Phase 1 Open-Label Study to Evaluate the Metabolism and Excretion of CC-223 and the Effect of Food on the Pharmacokinetics of CC-223 in Healthy Male Adult Subjects CC-223 - Safety and Pharmacokinetics in Healthy Volunteer Subjects | Phase 1 | Completed | 18 | 2012-06-01 | 2019-11-12 |
Study Assessing Safety, Pharmacokinetics and Efficacy of CC-223 With Either Erlotinib or Oral Azacitidine in Advanced Non-Small Cell Lung Cancer CC-223, erlotinib, CC-223, oral azacitidine - Carcinoma, Non-Small-Cell Lung, Non-Small Cell Lung Cancer | Phase 1 | Completed | 76 | 2012-05-01 | 2019-11-12 |
Study to Assess Safety, Pharmacokinetics, and Efficacy of Oral CC-223 for Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma or Multiple Myeloma CC-223 - Multiple Myeloma, Diffuse Large B-Cell Lymphoma | Phase 1 / Phase 2 | Completed | 226 | 2010-07-20 | 2022-12-13 |
Conditions studied
Carcinoma, Non-Small-Cell Lung (2) · Lymphoma, Large B-Cell, Diffuse (2) · Carcinoma, Hepatocellular (1) · Glioblastoma (1) · Lung Neoplasms (1) · Lymphoma (1) · Mineralocorticoid Excess Syndrome, Apparent (1) · Multiple Myeloma (1) · Neoplasms (1)
Sponsors
Celgene (5)
Countries
United States (4) · France (2) · Spain (2) · Canada (1) · Italy (1) · United Kingdom (1)
Top investigators
Edward O'Mara, MD (1) · Kristen Hege, MD (1) · Maria Palmisano, M.D. (1)