7 completed, 2 recruiting. 3 Phase 2, 3 Phase 3, 1 Not applicable, 1 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 2, Recruiting 1 |
| Phase 3 | 3 | Completed 3 |
| Not applicable | 1 | Completed 1 |
| Phase 1 | 1 | Recruiting 1 |
| Phase 4 | 1 | Completed 1 |
Follow benoxinate: new trials by email Literature Review of benoxinate trials Research Report on benoxinate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety, Tolerability, and Pharmacokinetic Profile of Grammidin With Anesthetic, a Metered Dose Topical Spray in Healthy Volunteers Grammidin with anesthetic neo, Grammidin with anesthetic, a metered dose topical spray - Pharyngitis | Phase 1 | Recruiting | Valenta Pharm JSC | 24 | 2024-12-09 | 2025-07-10 |
| Study to Evaluate the Efficacy and Safety of Different Doses of Graminidin With Anesthetic, a Metered Dose Topical Spray, in the Treatment of Acute Infectious and Inflammatory Pharyngeal Diseases Compared With Drug Septolete Total, Lozenges Grammidin with anesthetic, Septolete Total - Pharyngitis Acute, Pharyngitis | Phase 2 | Recruiting | Valenta Pharm JSC | 300 | 2024-11-14 | 2025-07-10 |
| Efficacy and Safety of Chloroprocaine 3% Gel and Oxybuprocaine 0.4% Eye Drops Anesthesia in Pediatric Population Chloroprocaine 3% eye gel, Oxybuprocaine Hydrochloride 4 Mg/mL Eye Drops - Local Anesthetic | Phase 3 | Completed | Sintetica SA | 74 | 2024-05-23 | 2026-03-09 |
| Hemodynamic Response to Pain During Retinopathy Of Prematurity Screening benoxinate hydrochloride 0.4% group, saline 0.9% . - Preterm | Phase 4 | Completed | Alexandria University | 68 | 2023-01-20 | 2025-02-05 |
| Effect of Benoxinate Hydrochloride Eye Drops on The Premature Infant Pain Profile Score During Retinopathy of Prematurity Screening Benoxinate Hydrochloride, artificial tear (Sodium Hyaluronate 2 mg/ml) eye drops. - Retinopathy of Prematurity | Phase 3 | Completed | Alexandria University | 88 | 2023-01-01 | 2024-06-17 |
| Effect of Four Different Diagnostic Eye Drops on Tear Film Thickness Oxybuprocaine MDU, Oxybuprocaine SDU, Oxybuprocaine/fluorescein SDU - Ocular Surface Disease, Tear Film Characteristics | Phase 3 | Completed | Medical University of Vienna | 20 | 2020-06-10 | 2025-11-17 |
| Optimization of Sampling and Processing of Samples for Molecular Microbial Research on Ocular Surface Samples Conjunctival swab, Oxybuprocaine Hydrochloride 0.4% Eye Drops, artificial tears - Microbiota, Ocular Surface | Not applicable | Completed | Universitaire Ziekenhuizen KU Leuven | 24 | 2019-08-19 | 2022-07-22 |
| Conscious Sedation for Cataract Operations Under Topical Anaesthesia Nalbuphine, Propofol, Dexmedetomidine - Conscious Sedation | Phase 2 | Completed | Menoufia University | 100 | 2019-07-01 | 2021-01-08 |
| Dexmedetomidine and Pregabalin for Conscious Sedation During Cataract Surgery Dexmedetomidine Injection, Placebo oral capsule, Pregabalin Oral Capsule - Conscious Sedation | Phase 2 | Completed | Abd-Elazeem Abd-Elhameed Elbakry | 60 | 2018-12-10 | 2019-12-27 |
Pharyngitis (2) · Nasopharyngitis (1) · Premature Birth (1) · Retinopathy of Prematurity (1)
Alexandria University (2) · Valenta Pharm JSC (2) · Abd-Elazeem Abd-Elhameed Elbakry (1) · Medical University of Vienna (1) · Menoufia University (1) · Sintetica SA (1) · Universitaire Ziekenhuizen KU Leuven (1)
Egypt (4) · Russia (2) · Austria (1) · Belgium (1) · Italy (1)
Abd-Elazeem A Elbakry, MD (2) · Heleen Delbeke, MD (1) · Hesham Ghazal, PhD (1) · Islam Ahmed, M.D. (1) · Shimaa Hafez, MBChB (1)