Bendamustine: Clinical Trials

54 trials of Bendamustine, newest first

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  

54 completed. 54 Phase 1, 23 Phase 2.

By phase and status

PhaseTrialsStatus
Phase 154Completed 54
Phase 223Completed 23

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Trials (filtered) newest first · largest first

All 54 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
FT522 With Rituximab in Relapsed/Refractory B-Cell Lymphoma (FT522-101)
FT522, Rituximab, Cyclophosphamide - Relapsed/Refractory B-Cell Lymphoma
Phase 1CompletedFate Therapeutics202023-11-162025-08-22
FT576 in Subjects With Multiple Myeloma
FT576 (Allogenic CAR NK cells with BCMA expression), Cyclophosphamide, Fludarabine - Multiple Myeloma, Myeloma
Phase 1CompletedFate Therapeutics312021-11-102025-12-12
AB-101 as Monotherapy and With Immunotherapy in Patients With Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma
AB-101, Rituximab, Interleukin-2 - Non Hodgkin Lymphoma
Phase 1 / Phase 2CompletedArtiva Biotherapeutics, Inc.452021-03-292026-04-03
A Study of CC-95266 in Participants With Relapsed and/or Refractory Multiple Myeloma
CC-95266, Fludarabine, Cyclophosphamide - Multiple Myeloma
Phase 1CompletedJuno Therapeutics, a Subsidiary of Celgene1302021-02-242026-02-09
Gemcitabine, Bendamustine, and Nivolumab in Patients With Relapsed or Refractory Classical Hodgkin Lymphoma
Bendamustine, Gemcitabine, Nivolumab - Recurrent Hodgkin Lymphoma, Refractory Hodgkin Lymphoma
Phase 1 / Phase 2CompletedEmory University32018-11-262025-08-06
Haploidentical Stem Cell Transplant with Prophylactic Natural Killer DLI for Lymphoma, Multiple Myeloma, and CLL
Total Body Irradiation, Haploidentical Stem Cell Transplantation, CD56-Enriched Donor Lymphocyte Infusion - Multiple Myeloma, CLL
Phase 1CompletedNoah Merin202018-07-182024-11-12
INCB050465 in Combination With Rituximab, Bendamustine and Rituximab, or Ibrutinib in Participants With Previously Treated B-Cell Lymphoma (CITADEL-112)
Parsaclisib, Rituximab, Bendamustine - B-cell Lymphoma
Phase 1CompletedIncyte Corporation502018-07-022025-08-21
Vincristine Sulfate Liposome Injection (Marqibo®), Bendamustine and Rituximab-Phase I Trial in Indolent B-cell Lymphoma
Rituximab, Bendamustine, Vincristine sulfate liposome injection - Lymphoma, Non-Hodgkin, Lymphoma, Follicular
Phase 1CompletedBrown University112017-05-102023-02-09
Study Evaluating Safety and Efficacy of INCB050465 Combined With Bendamustine and Obinutuzumab in Relapsed or Refractory Follicular Lymphoma (CITADEL-102)
Parsaclisib, Hexal, Gazyvaro - Lymphoma
Phase 1CompletedIncyte Corporation262017-02-152025-08-21
Haploidentical BMT With Post-Transplant Cyclophosphamide and Bendamustine
Bendamustine, Cyclophosphamide - Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia
Phase 1CompletedUniversity of Arizona502016-11-292025-11-10
GVHD Prophylaxis With Post-transplantation Bendamustine in Refractory Leukemia
Allogeneic stem cell transplantation, Fludarabine monophosphate, Busulfan - Leukemia, Acute Lymphoblastic, Acute Myeloid Leukemia
Phase 1 / Phase 2CompletedSt. Petersburg State Pavlov Medical University272016-06-012020-11-23
A Study to Determine Dose, Safety, and Efficacy of Durvalumab as Monotherapy and in Combination Therapy in Subjects With Lymphoma or Chronic Lymphocytic Leukemia
Durvalumab, Lenalidomide, Rituximab - Lymphoma, Leukemia, Lymphocytic, Chronic, B-Cell
Phase 1 / Phase 2CompletedCelgene1062016-05-112023-11-18
Bendamustine and Rituximab Alternating With Cytarabine and Rituximab for Untreated Mantle Cell Lymphoma
Bendamustine, Rituximab, Cytarabine - Mantle Cell Lymphoma
Phase 1CompletedWashington University School of Medicine182016-04-182023-11-01
Hodgkin Lymphoma Treatment With Adcetris and Levact in the Old Patient
Adcetris-Levact - Clinical Efficacy, Safety
Phase 1 / Phase 2CompletedCentre Antoine Lacassagne602016-01-142026-08-31
A Study of Atezolizumab in Combination With Either Obinutuzumab Plus Bendamustine or Obinutuzumab Plus (+) Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) in Participants With Follicular Lymphoma (FL) or Rituximab + CHOP in Participants With Diffuse Large B-Cell Lymphoma (DLBCL)
Atezolizumab, Bendamustine, Cyclophosphamide - Diffuse Large B-Cell Lymphoma, Lymphoma Follicular
Phase 1 / Phase 2CompletedHoffmann-La Roche912015-12-222021-05-24
Carfilzomib With Bendamustine and Rituximab in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma
Carfilzomib, Bendamustine, Rituximab - Lymphoma, Non-Hodgkin, Lymphoma
Phase 1CompletedUniversity of California, San Francisco102015-05-052021-04-23
Study Evaluating the Safety and Efficacy of KTE-C19 in Adult Participants With Refractory Aggressive Non-Hodgkin Lymphoma
Axicabtagene Ciloleucel, Fludarabine, Cyclophosphamide - Refractory Diffuse Large B Cell Lymphoma (DLBCL), Relapsed Diffuse Large B-Cell Lymphoma
Phase 1 / Phase 2CompletedKite, A Gilead Company3072015-04-212024-06-04
A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma
Bendamustine, Obinutuzumab, Polatuzumab vedotin (Liquid) - Lymphoma
Phase 1 / Phase 2CompletedHoffmann-La Roche3312014-10-152022-11-14
A Pilot Study of Immunotherapy Including Haploidentical NK Cell Infusion Following CD133+ Positively-Selected Autologous Hematopoietic Stem Cells in Children With High Risk Solid Tumors or Lymphomas
CD133+ selected autologous stem cell infusion, IL-2, hu14.18K322A - Neuroblastoma, Lymphoma
Phase 1CompletedSt. Jude Children's Research Hospital82014-10-102017-12-22
Everolimus and Bendamustine Hydrochloride in Treating Patients With Relapsed or Refractory Hematologic Cancer
everolimus, bendamustine hydrochloride - Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Hodgkin Lymphoma
Phase 1CompletedUniversity of California, Davis202014-10-012019-01-04

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Conditions studied

Leukemia, Lymphocytic, Chronic, B-Cell (16)  ·  Lymphoma, Non-Hodgkin (15)  ·  Lymphoma (13)  ·  Hodgkin Disease (11)  ·  Lymphoma, Follicular (10)  ·  Lymphoma, Mantle-Cell (8)  ·  Multiple Myeloma (7)  ·  Lymphoma, B-Cell, Marginal Zone (6)  ·  Lymphoma, Large B-Cell, Diffuse (6)  ·  Leukemia (4)  ·  Lymphoma, B-Cell (4)  ·  Recurrence (4)  ·  Neoplasms (3)  ·  Precursor Cell Lymphoblastic Leukemia-Lymphoma (3)  ·  Breast Neoplasms (2)

Sponsors

Hoffmann-La Roche (3)  ·  M.D. Anderson Cancer Center (3)  ·  Aptevo Therapeutics (2)  ·  Cephalon (2)  ·  Fate Therapeutics (2)  ·  Genentech, Inc. (2)  ·  Incyte Corporation (2)  ·  St. Jude Children's Research Hospital (2)  ·  Weill Medical College of Cornell University (2)  ·  AbbVie (1)  ·  Alliance for Clinical Trials in Oncology (1)  ·  Arbeitsgemeinschaft medikamentoese Tumortherapie (1)  ·  Artiva Biotherapeutics, Inc. (1)  ·  Beth Christian (1)  ·  Brown University (1)

Countries

United States (47)  ·  France (6)  ·  Germany (6)  ·  Italy (6)  ·  Spain (5)  ·  Australia (4)  ·  Canada (4)  ·  Netherlands (4)  ·  United Kingdom (3)  ·  Austria (2)  ·  Czechia (2)  ·  Hungary (2)  ·  Israel (2)  ·  Poland (2)  ·  Russia (2)

Top investigators

Scott Stromatt, MD (2)  ·  Adam J Olszewski, MD (1)  ·  Alexey V Danilov, MD (1)  ·  Apostolia M. Tsimberidou, MD, PhD (1)  ·  Beth Christian, MD (1)  ·  Boris V. Afanasyev, Professor (1)  ·  Brad S Kahl, M.D. (1)  ·  Brandon M. Triplett, MD (1)  ·  Charalambos Andreadis, M.D. (1)  ·  Emmanuel Katsanis, MD (1)

Results publications

PMID 19860608, PMID 21816833, PMID 22451423, PMID 23430121, PMID 23843495, PMID 25145344, PMID 25769620, PMID 26331432, PMID 26659915, PMID 28011903, PMID 29226797, PMID 29276022, PMID 29296805, PMID 29703778, PMID 29908231, PMID 30518502, PMID 31050355, PMID 31190006, PMID 31693429, PMID 31723767, PMID 32126141, PMID 32582591, PMID 32705923, PMID 32770353, PMID 33028076, PMID 33035333, PMID 33334730, PMID 33478921, PMID 33586581, PMID 33598942, PMID 34296427, PMID 34310745, PMID 34493319, PMID 34515338, PMID 34749395, PMID 35086141, PMID 35359000, PMID 35460929, PMID 35641232, PMID 35847727, PMID 35852004, PMID 36287231, PMID 36821768, PMID 37981564, PMID 38598516, PMID 38635762, PMID 38843483, PMID 39240498, PMID 40270968, PMID 42233419

NIH funding

2015 (3), 2008 (1), 2014 (1), 2016 (1), 2017 (1), K12CA076930 (1), P30CA012197 (1), P30CA016672 (1), P30CA023108 (1), P30CA138292 (1)