belzutifan: Clinical Trials

8 trials of belzutifan, newest first

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5 active not recruiting, 3 recruiting. 8 Phase 3.

By phase and status

PhaseTrialsStatus
Phase 38Active not recruiting 5, Recruiting 3

Follow belzutifan: new trials by email Literature Review of belzutifan trials Research Report on belzutifan

Trials (filtered) newest first · largest first

All 8 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
A Clinical Study of Belzutifan (MK-6482) and Zanzalintinib in People With Renal Cell Carcinoma (RCC) (LITESPARK-034/LS-034/MK-6482-034)
Belzutifan, Zanzalintinib, Placebo - Carcinoma, Renal Cell
Phase 3RecruitingMerck Sharp & Dohme LLC7582026-04-092026-10-29
Extension Study for Participants in Studies That Include Belzutifan (MK-6482-043/LITESPARK-043)
Belzutifan, Nivolumab, Lenvatinib - Von Hippel-Lindau Disease, Malignant Neoplasms
Phase 3RecruitingMerck Sharp & Dohme LLC4502026-03-232026-10-21
A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)
Belzutifan, Zanzalintinib, Cabozantinib - Renal Cell Carcinoma
Phase 3RecruitingMerck Sharp & Dohme LLC9042025-11-262026-08-03
A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, vs Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)-China Extension Study
Pembrolizumab, Belzutifan, Pembrolizumab/Quavonlimab - Carcinoma, Renal Cell
Phase 3Active not recruitingMerck Sharp & Dohme LLC2512022-07-272026-08-20
A Study of Belzutifan (MK-6482) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Clear Cell Renal Cell Carcinoma Post Nephrectomy (MK-6482-022)
Belzutifan, Pembrolizumab, Placebo - Carcinoma, Renal Cell
Phase 3Active not recruitingMerck Sharp & Dohme LLC18002022-03-152026-05-15
A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, Versus Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)
Pembrolizumab, Belzutifan, Pembrolizumab/Quavonlimab - Carcinoma, Renal Cell
Phase 3Active not recruitingMerck Sharp & Dohme LLC16882021-04-142026-10-02
A Study of Belzutifan (MK-6482) in Combination With Lenvatinib Versus Cabozantinib for Treatment of Renal Cell Carcinoma (MK-6482-011)
Belzutifan, Lenvatinib, Cabozantinib - Carcinoma, Renal Cell
Phase 3Active not recruitingMerck Sharp & Dohme LLC7472021-02-252026-05-05
A Study of Belzutifan (MK-6482) Versus Everolimus in Participants With Advanced Renal Cell Carcinoma (MK-6482-005)
Belzutifan, Everolimus - Carcinoma, Renal Cell
Phase 3Active not recruitingMerck Sharp & Dohme LLC7552020-02-272026-10-20

Conditions studied

Carcinoma, Renal Cell (7)  ·  Parkinson Disease 4, Autosomal Dominant Lewy Body (3)  ·  Carcinoma (1)  ·  Kidney Neoplasms (1)  ·  Neoplasms (1)  ·  von Hippel-Lindau Disease (1)

Sponsors

Merck Sharp & Dohme LLC (8)

Countries

Brazil (7)  ·  Chile (7)  ·  Czechia (7)  ·  France (7)  ·  South Korea (7)  ·  Spain (7)  ·  United Kingdom (7)  ·  United States (7)  ·  Australia (6)  ·  Canada (6)  ·  Germany (6)  ·  Italy (6)  ·  Poland (6)  ·  Denmark (5)  ·  Finland (5)

Results publications

PMID 36064785, PMID 36752726, PMID 37882432, PMID 39167807, PMID 40112850, PMID 42384869, PMID 42586114

NIH funding

2023 (2), 2019 (1), 2025 (1)