2 enrolling by invitation, 2 recruiting. 4 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Enrolling by invitation 2, Recruiting 2 |
| Phase 2 | 4 | Enrolling by invitation 2, Recruiting 2 |
Follow Base-edited hematopoietic stem and progenitor cells: new trials by email Literature Review of Base-edited hematopoietic stem and progenitor cells trials Research Report on Base-edited hematopoietic stem and progenitor cells
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Base-Edited Hematopoietic Stem/Progenitor Cell Gene Therapy for Treatment of CXCR4-WHIM Busulfan, Palifermin, Plerixafor - WHIM, Warts | Phase 1 / Phase 2 | Enrolling by invitation | National Institute of Allergy and Infectious Diseases (NIAID) | 10 | 2026-10-21 | 2026-10-27 |
| Base Editing Hematopoietic Stem Cell and T Cell Gene Therapy for CD40L-HyperIgM Syndrome: Single Patient Study Base-edited hematopoietic stem and progenitor cells, Alemtuzumab, Sirolimus - CD40L-HyperIgM Syndrome | Phase 1 / Phase 2 | Recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 1 | 2025-07-16 | 2026-07-31 |
| Base-Edited Hematopoietic Stem/Progenitor Cell X-Linked Severe Combined Immunodeficiency Gene Therapy Plerixafor, Filgrastim, Palifermin - X-linked Severe Combined Immunodeficiency, X-SCID | Phase 1 / Phase 2 | Enrolling by invitation | National Institute of Allergy and Infectious Diseases (NIAID) | 18 | 2025-05-09 | 2026-10-13 |
| Base Editing for Mutation Repair in Hematopoietic Stem & Progenitor Cells for X-Linked Chronic Granulomatous Disease Campath, Sirolimus, Base-edited hematopoietic stem and progenitor cells - Chronic Granulomatous Disease (CGD), X-Linked Chronic Granulomatous Disease | Phase 1 / Phase 2 | Recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 15 | 2024-04-17 | 2026-08-13 |
Agammaglobulinemia (1) · Granulomatous Disease, Chronic (1) · Immunologic Deficiency Syndromes (1) · Warts (1) · X-Linked Combined Immunodeficiency Diseases (1)
National Institute of Allergy and Infectious Diseases (NIAID) (4)
United States (4)