5 completed, 1 not yet recruiting, 1 terminated, 1 withdrawn. 5 Phase 1, 4 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 3, Not yet recruiting 1, Withdrawn 1 |
| Phase 2 | 4 | Completed 3, Withdrawn 1 |
| Phase 3 | 1 | Terminated 1 |
Follow balixafortide: new trials by email Literature Review of balixafortide trials Research Report on balixafortide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase I Study of Cosibelimab and Balixafortide in Metastatic Pancreatic Ductal Adenocarcinoma Balixafortide, Cosibelimab - Metastatic Pancreatic Ductal Adenocarcinoma | Phase 1 | Not yet recruiting | Arsen Osipov | 24 | 2026-01-01 | 2025-11-19 |
| POL6326 (Balixafortide) Plus Nab-paclitaxel or Eribulin in Patients With HER2-negative Advanced Breast Cancer POL6326, Eribulin, Nab paclitaxel - Advanced Breast Cancer | Phase 1 / Phase 2 | Withdrawn | MedSIR | 2022-03-16 | 2023-03-20 | |
| Pivotal Study in HER2 Negative, Locally Recurrent or Metastatic Breast Cancer Eribulin, Balixafortide - Metastatic Breast Cancer, Locally Recurrent Breast Cancer | Phase 3 | Terminated | Spexis AG | 432 | 2019-05-30 | 2023-11-01 |
| CXCR4 Antagonism for Cell Mobilisation and Healing in Acute Myocardial Infarction (CATCH-AMI) POL6326, Placebo - Large Reperfused ST-Elevation Myocardial Infarction | Phase 2 | Completed | Polyphor Ltd. | 120 | 2013-07-01 | 2016-06-10 |
| Dose Escalation of POL6326 in Combination With Eribulin in Patients With Metastatic Breast Cancer POL6326 - Metastatic Breast Cancer | Phase 1 | Completed | Polyphor Ltd. | 54 | 2013-06-01 | 2018-09-14 |
| Safety and Efficacy of POL6326 for Mobilization/Transplant of Sibling Donor in Patients With Hematologic Malignancies POL6326, Leukapheresis, PBSC Transplant - Acute Myeloid Leukemia in Remission, Adult Acute Lymphoblastic Leukemia in Remission | Phase 1 / Phase 2 | Completed | Polyphor Ltd. | 38 | 2012-04-01 | 2016-02-26 |
| Safety and Efficacy of POL6326 for Mobilization of Hematopoietic Stem Cells in Healthy Volunteers POL6326 - Healthy | Phase 1 | Completed | Polyphor Ltd. | 27 | 2012-02-01 | 2015-11-25 |
| Exploratory Study on POL6326 in Stem Cell Mobilization POL6326 - Multiple Myeloma | Phase 2 | Completed | Polyphor Ltd. | 21 | 2009-04-01 | 2014-04-23 |
Breast Neoplasms (2) · Multiple Myeloma (2) · Hodgkin Disease (1) · Leukemia, Lymphocytic, Chronic, B-Cell (1) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (1) · Lymphoma, Non-Hodgkin (1) · Myelodysplastic Syndromes (1) · Myeloproliferative Disorders (1) · ST Elevation Myocardial Infarction (1)
Polyphor Ltd. (5) · Arsen Osipov (1) · MedSIR (1) · Spexis AG (1)
United States (4) · Germany (3) · Spain (2) · United Kingdom (2) · Argentina (1) · Austria (1) · Belgium (1) · Brazil (1) · Czechia (1) · France (1) · Hungary (1) · Italy (1) · Poland (1) · Russia (1) · South Korea (1)
Arsen Osipov, MD (1) · Daniel Couriel, M.D. (1) · Halvard Boenig, M.D. Ph.D (1) · Hartmut Goldschmidt, MD (1) · Javier Cortes, MD (1) · Kai C. Wollert, MD (1) · Peter A Kaufman, MD (1) · Peter Kaufman, MD (1)