12 completed, 1 terminated. 12 Phase 4, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 12 | Completed 11, Terminated 1 |
| Phase 3 | 1 | Completed 1 |
Follow Azarga: new trials by email Literature Review of Azarga trials Research Report on Azarga
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Assessing the Efficacy and Tolerability of AZARGA® (Brinzolamide 1%/Timolol 0.5% Fixed Combination) as Replacement Therapy in Patients on COMBIGAN® (Brimonidine 0.2%/Timolol 0.5% Fixed Combination) Therapy in Brazil Brinzolamide/timolol maleate fixed combination - Glaucoma | Phase 4 | Terminated | Alcon Research | 9 | 2012-03-01 | 2013-10-21 |
| Assessing the Efficacy and Tolerability of AZARGA® (Brinzolamide 1%/Timolol 0.5% Fixed Combination) as Replacement Therapy in Patients on Brimonidine 0.2%/Timolol 0.5% Fixed Combination Therapy (COMBIGAN®) in Latin America Brinzolamide/timolol maleate fixed combination - Glaucoma | Phase 4 | Completed | Alcon Research | 50 | 2011-12-01 | 2015-08-07 |
| Efficacy and Tolerability of AZARGA® as Replacement Therapy in Patients on COMBIGAN® Therapy in Canada Brinzolamide 1% / timolol 0.5% maleate fixed combination - Glaucoma, Ocular Hypertension | Phase 4 | Completed | Alcon Research | 57 | 2011-09-01 | 2014-07-01 |
| Patient Preference Comparison of AZARGA Versus COSOPT Brinzolamide 1.0% + Timolol 0.5% ophthalmic suspension, Dorzolamide 2.0% + Timolol 0.5% ophthalmic solution - Open-Angle Glaucoma, Ocular Hypertension | Phase 4 | Completed | Alcon Research | 112 | 2011-09-01 | 2014-02-10 |
| AZARGA Transition Study in Taiwan for Patients With Uncontrolled Intraocular Pressure Brinzolamide 1% and timolol 0.5% fixed combination eye drops - Glaucoma | Phase 4 | Completed | Alcon Research | 74 | 2011-05-01 | 2013-05-01 |
| Safety and Efficacy of Adding AZARGA® Adjunctive to Prostaglandin Therapy Brinzolamide 1% / timolol 0.5% Fixed Combination, Habitual prostaglandin monotherapy - Glaucoma, Ocular Hypertension | Phase 4 | Completed | Alcon Research | 47 | 2011-03-01 | 2014-05-20 |
| Fixed Combination Brinzolamide 1%/Timolol 0.5% Versus Brinzolamide 1% + Timolol 0.5% in Open-Angle Glaucoma or Ocular Hypertension Brinzolamide 1% / Timolol 0.5% fixed combination ophthalmic suspension, Brinzolamide 1% ophthalmic suspension, Timolol 0.5% ophthalmic solution - Open-Angle Glaucoma, Ocular Hypertension | Phase 3 | Completed | Alcon Research | 328 | 2010-11-01 | 2014-04-10 |
| Patient Preference Comparison of AZARGA Versus COSOPT in Patients With Glaucoma Brinzolamide/Timolol Maleate Fixed Combination (AZARGA), Dorzolamide/timolol Maleate Fixed Combination (COSOPT) - Glaucoma | Phase 4 | Completed | Alcon Research | 120 | 2010-09-01 | 2016-11-21 |
| Comparison of the Efficacy of AZARGA® Versus COSOPT® in Patients With Open-Angled Glaucoma or Ocular Hypertension Azarga (brinzolamide 1% / timolol 0.5%), Cosopt (dorzolamide 2% / timolol 0.5%) - Glaucoma, Ocular Hypertension | Phase 4 | Completed | Alcon Research | 70 | 2010-04-01 | 2015-07-29 |
| ELAZOP Switching Study in Korea Elazop (Azarga) - Open Angle Glaucoma | Phase 4 | Completed | Alcon Research | 96 | 2010-03-01 | 2012-12-17 |
| 24-Hour Intraocular Pressure With Brinzolamide/Timolol Versus Brimonidine/Timolol Brimonidine/timolol fixed combination drops added to travoprost, Brinzolamide/timolol fixed combination drops added to travoprost - Glaucoma | Phase 4 | Completed | Aristotle University Of Thessaloniki | 51 | 2009-08-01 | 2020-12-17 |
| Efficacy and Safety of Adding Azarga to Prostaglandin Monotherapy Brinzolamide/Timolol Maleate Fixed Combination (AZARGA) - Glaucoma | Phase 4 | Completed | Alcon Research | 47 | 2009-07-01 | 2016-11-21 |
| Circadian Ocular Perfusion Pressure and Ocular Blood Flow Brinzolamide 10 mg/ml/Timolol 5 mg/ml eye drops suspension, Brimonidine 20 mg/ml/Timolol 5 mg/ml eye drops solution - Glaucoma | Phase 4 | Completed | Alcon Research | 35 | 2009-02-01 | 2013-03-22 |
Glaucoma (12) · Glaucoma, Open-Angle (9) · Ocular Hypertension (9)
Alcon Research (12) · Aristotle University Of Thessaloniki (1)
United States (2) · Argentina (1) · Brazil (1) · Canada (1) · Germany (1) · South Korea (1)
Abayomi Ogundele, PharmD (1) · Anastasios G Konstas, MD, PhD (1) · Danyel C. Carr, MS, CCRA (1) · Doug Hubatsch (1) · Doug Hubatsch, M.Sc. (1) · Mandy Ye, MS (1) · Severine Durier, Pharm. D (1) · Severine Durier, Pharm.D (1)