12 completed, 2 unknown. 14 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 14 | Completed 12, Unknown 2 |
Follow Asparaginase: new trials by email Literature Review of Asparaginase trials Research Report on Asparaginase
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Combination Chemotherapy Including Cisplatin, Ifosfamide, Gemcitabine, L-asparaginase, Etoposide and Dexamethasone as Treatment of Newly Diagnosed and Relapsed/Refractory Peripheral T Cell Lymphomas cisplatin, ifosfamide, gemcitabine - Peripheral T Cell Lymphoma | Phase 4 | Unknown | The University of Hong Kong | 50 | 2017-02-24 | 2018-06-11 |
| Rituximab Plus Chemotherapy for CD20+ Adult Acute Lymphoblastic Leukemia Cyclophosphamide, Doxorubicin, Vincristine - Acute Lymphoblastic Leukemia | Phase 4 | Completed | Ruijin Hospital | 100 | 2010-12-01 | 2014-05-20 |
| Malaysia-Singapore Acute Lymphoblastic Leukemia 2010 Study Prednisolone, Dexamethasone, L-Asparaginase - Acute Lymphoblastic Leukemia (ALL) | Phase 4 | Unknown | National University Hospital, Singapore | 500 | 2008-10-01 | 2016-09-30 |
| Pethema LAL-RI/2008: Treatment for Patients With Standard Risk Acute Lymphoblastic Leukemia Vincristine, Daunorubicin, Prednisone - Acute Lymphobkastic Leukemia | Phase 4 | Completed | PETHEMA Foundation | 107 | 2008-01-01 | 2020-03-05 |
| LAL-AR-N-2005:Study Treatment for Children High Risk Acute Lymphoblastic Leukemia Prednisolone, Daunorubicin, Vincristine - Acute Lymphoblastic Leukemia | Phase 4 | Completed | PETHEMA Foundation | 40 | 2005-06-01 | 2014-10-28 |
| German Multicenter Trial for the Treatment of Newly Diagnosed T-lymphoblastic Lymphoma in Adults Dexamethasone/Prednisolone, Cyclophosphamide, Vincristine - Lymphoma, Lymphoblastic | Phase 4 | Completed | Johann Wolfgang Goethe University Hospital | 75 | 2004-04-01 | 2010-08-23 |
| Trial for Treatment of Adult Patients With Standard Risk Acute Lymphoblastic Leukemia With Chemotherapy and Rituximab Cyclophosphamide, Dexamethasone / Prednisolone, Vincristine - Adult Acute Lymphocytic Leukemia | Phase 4 | Completed | Johann Wolfgang Goethe University Hospital | 60 | 2004-04-01 | 2010-08-23 |
| German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (07/2003) Cyclophosphamide, Dexamethasone, Vincristine - Adult Acute Lymphocytic Leukemia | Phase 4 | Completed | Goethe University | 1883 | 2003-04-01 | 2022-08-18 |
| German Multicenter Trial for Treatment of Elderly Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Cyclophosphamide, Dexamethasone / Prednisolone, Cytarabine - Adult Acute Lymphocytic Leukemia | Phase 4 | Completed | Goethe University | 377 | 2003-01-01 | 2023-03-20 |
| LAL-BR/2001: Study Treatment to Low Risk ALL Prednisone, Vincristine, Daunorubicin - Acute Lymphoblastic Leukemia | Phase 4 | Completed | PETHEMA Foundation | 150 | 2001-06-01 | 2016-01-20 |
| LAL-Ph-2000: Treatment of Acute Lymphoblastic Leukemia Chromosome Philadelphia Positive Vincristine, Daunorubicin, Prednisone - Acute Lymphoblastic Leukemia | Phase 4 | Completed | PETHEMA Foundation | 100 | 2000-01-01 | 2010-01-05 |
| German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (06/99) Dexamethasone / Prednisolone, Cyclophosphamide, Methotrexate - Adult Acute Lymphocytic Leukemia | Phase 4 | Completed | Goethe University | 225 | 1999-10-01 | 2023-03-20 |
| PETHEMA LAL-RI/96: Treatment for Patients With Standard Risk Acute Lymphoblastic Leukemia Asparaginase, Cyclophosphamide, Cytarabine - Acute Lymphoblastic Leukemia | Phase 4 | Completed | PETHEMA Foundation | 374 | 1996-06-01 | 2009-05-19 |
| German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (05/93) Asparaginase, Vincristine, Daunorubicin, Adriamycin - Adult Acute Lymphocytic Leukemia | Phase 4 | Completed | Goethe University | 720 | 1993-04-01 | 2023-03-17 |
Precursor Cell Lymphoblastic Leukemia-Lymphoma (12) · Neoplasm, Residual (3) · Lymphoma (1) · Lymphoma, T-Cell, Peripheral (1)
PETHEMA Foundation (5) · Goethe University (4) · Johann Wolfgang Goethe University Hospital (2) · National University Hospital, Singapore (1) · Ruijin Hospital (1) · The University of Hong Kong (1)
Germany (6) · Spain (5) · China (1) · Hong Kong (1) · Malaysia (1) · Singapore (1)
Dieter Hoelzer, MD,PhD (4) · Bastida Pilar, Dr (2) · Dieter Hoelzer, MD, PhD (2) · Allen Yeoh, MBBS (1) · Weili Zhao, MD,PhD (1) · Yok Lam Kwong, MBBS (1)
PMID 19144982, PMID 22442346, PMID 22493293, PMID 23024237, PMID 27561722, PMID 28751559, PMID 30044693, PMID 37276496, PMID 42477805