6 completed, 1 unknown. 6 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 5, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
Follow AR-12286: new trials by email Literature Review of AR-12286 trials Research Report on AR-12286
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Compassionate Case Study to Assess the Hypotensive Efficacy of Rho-Kinase Inhibitor AR-12286 Ophthalmic Solution 0.5% and 0.7% in Glaucoma Patients With Uncontrolled Intraocular Pressure to Avoid Surgical Intervention Rho-Kinase Inhibitor (AR-12286) - Glaucoma | Phase 2 | Unknown | New York Glaucoma Research Institute | 10 | 2014-06-01 | 2015-04-24 |
| A Prospective Study to Assess the Hypotensive Efficacy of Rho-Kinase Inhibitor AR-12286 Ophthalmic Solution 0.5% and 0.7% in Patients With Exfoliation Syndrome and Ocular Hypertension or Glaucoma AR-12286 - Exfoliation Syndrome, Ocular Hypertension | Phase 2 | Completed | Robert Ritch, MD, LLC. | 10 | 2013-09-01 | 2018-11-16 |
| AR-12286 Fixed Dose Combination to Lower Elevated Intraocular Pressure 0.25% AR-12286 / 0.004% travoprost, 0.5% AR-12286, 0.004% travoprost, 0.004% Travoprost - Glaucoma, Ocular Hypertension | Phase 2 | Completed | Aerie Pharmaceuticals | 93 | 2011-12-01 | 2016-09-23 |
| 24-hour Efficacy of AR-12286 AR-12286 0.5% Ophthalmic Solution - Open Angle Glaucoma, Ocular Hypertension | Phase 2 | Completed | Aerie Pharmaceuticals | 5 | 2011-05-01 | 2014-04-21 |
| Formulation Comparison in Normal Volunteers AR-12286 - Normal Volunteers | Phase 1 | Completed | Aerie Pharmaceuticals | 18 | 2010-11-01 | 2010-12-22 |
| Study of AR-12286 Versus Latanoprost in Patients With Elevated Intraocular Pressure AR-12286 0.5% ophthalmic solution, AR-12286 0.25% Ophthalmic solution, Latanoprost ophthalmic solution - Glaucoma | Phase 2 | Completed | Aerie Pharmaceuticals | 217 | 2010-02-01 | 2014-05-08 |
| A Study of AR-12286 in Patient With Elevated Intraocular Pressure (IOP) AR-12286, AR-12286 vehicle - Elevated Intraocular Pressure | Phase 2 | Completed | Aerie Pharmaceuticals | 89 | 2009-05-01 | 2014-04-21 |
Glaucoma (4) · Ocular Hypertension (4) · Glaucoma, Open-Angle (2) · Exfoliation Syndrome (1)
Aerie Pharmaceuticals (5) · New York Glaucoma Research Institute (1) · Robert Ritch, MD, LLC. (1)
United States (7)
Tom van Haarlem, MD (2) · Thomas van Haarlem, MD (1)