5 completed, 1 active not recruiting. 6 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Completed 5, Active not recruiting 1 |
Follow afamelanotide: new trials by email Literature Review of afamelanotide trials Research Report on afamelanotide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Compare the Efficacy and Safety of SCENESSE and Narrow-Band Ultraviolet (NB-UVB) Light Versus NB-UVB Light Alone in Patients With Vitiligo Afamelanotide and NB-UVB Light, NB-UVB Light - Vitiligo | Phase 3 | Active not recruiting | Clinuvel, Inc. | 200 | 2023-10-11 | 2025-07-08 |
| Phase III Confirmatory Study in Erythropoietic Protoporphyria Afamelanotide, Placebo - Erythropoietic Protoporphyria | Phase 3 | Completed | Clinuvel Pharmaceuticals Limited | 93 | 2012-05-01 | 2019-09-19 |
| A Safety Extension Study in Patients With Erythropoietic Protoporphyria (EPP) Afamelanotide - Erythropoietic Protoporphyria | Phase 3 | Completed | Clinuvel Pharmaceuticals Limited | 16 | 2011-07-11 | 2020-11-19 |
| Afamelanotide in Patients Suffering From Polymorphic Light Eruption (PLE) Afamelanotide, Placebo - Polymorphic Light Eruption | Phase 3 | Completed | Clinuvel Pharmaceuticals Limited | 31 | 2010-05-05 | 2021-03-19 |
| Phase III Confirmatory Study in Erythropoietic Protoporphyria (EPP) Afamelanotide, Placebo - Erythropoietic Protoporphyria | Phase 3 | Completed | Clinuvel Pharmaceuticals Limited | 74 | 2009-09-01 | 2021-10-12 |
| Multicentre Phase III Erythropoietic Protoporphyria Study Afamelanotide, Placebo - Erythropoietic Protoporphyria | Phase 3 | Completed | Clinuvel Pharmaceuticals Limited | 100 | 2007-05-01 | 2019-10-10 |
Protoporphyria, Erythropoietic (4) · Vitiligo (1)
Clinuvel Pharmaceuticals Limited (5) · Clinuvel, Inc. (1)
France (2) · United Kingdom (2) · United States (2) · Finland (1) · Germany (1) · Ireland (1) · Kenya (1) · Netherlands (1)
Alex Anstey, MBBS, FRCP (1) · Eric JG Sijbrands, MD, PhD (1) · Gillian M Murphy, MD PhD (1) · Jean-Charles Deybach, MD. PhD (1) · Jorge Frank, MD, PhD (1) · Lesley E Rhodes, MD PhD (1) · Pilar Bilbao (1) · Raili Kauppinen, MD, PhD (1) · Robert Desnick, MD (1) · Sandra Hanneken, MD (1)