4 completed, 1 not yet recruiting, 1 recruiting. 5 Phase 3, 3 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Completed 3, Not yet recruiting 1, Recruiting 1 |
| Phase 2 | 3 | Completed 3 |
| Phase 1 | 1 | Completed 1 |
Follow Acoziborole: new trials by email Literature Review of Acoziborole trials Research Report on Acoziborole
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Stop Transmission of Gambiense Human African Trypanosomiasis (STROgHAT) Treatment of seropositive individuals (positive serology test, but parasitology not confirmed) - Human African Trypanosomiasis | Phase 3 | Not yet recruiting | Drugs for Neglected Diseases | 2500 | 2024-04-08 | 2024-04-10 |
| Stop Transmission of Gambiense Human African Trypanosomiasis Acoziborole - Trypanosomiasis; African, Due to Trypanosoma Brucei Gambiense, Gambiense | Phase 3 | Recruiting | Institute of Tropical Medicine, Belgium | 2500 | 2024-03-15 | 2026-08-27 |
| DDI Study of Single Oral Dose of Acoziborole With Sequential Co-administration of Midazolam and Dextromethorphan Acoziborole, Midazolam, Dextromethorphan - Trypanosomiasis, African | Phase 1 | Completed | Drugs for Neglected Diseases | 20 | 2023-02-09 | 2023-07-17 |
| Pharmacokinetic, Efficacy, Safety and Tolerability Study of a Single Dose of Acoziborole in g-HAT Paediatric Patients Acoziborole - Trypanosomiasis, African, Trypanosoma Brucei Gambiense; Infection | Phase 2 / Phase 3 | Completed | Drugs for Neglected Diseases | 35 | 2022-07-09 | 2026-04-06 |
| Safety and Tolerability Study of Acoziborole in g-HAT Seropositive Subjects Acoziborole, Placebo - Trypanosomiasis, African, Trypanosoma Brucei Gambiense; Infection | Phase 2 / Phase 3 | Completed | Drugs for Neglected Diseases | 1208 | 2021-12-30 | 2025-03-20 |
| Efficacy and Safety of Acoziborole (SCYX-7158) in Patients With Human African Trypanosomiasis Due to T.b. Gambiense Acoziborole - Trypanosomiasis, African, Gambiense Trypanosomiasis | Phase 2 / Phase 3 | Completed | Drugs for Neglected Diseases | 208 | 2016-10-11 | 2025-09-17 |
Trypanosomiasis, African (4) · Infections (2) · Trypanosomiasis (1)
Drugs for Neglected Diseases (5) · Institute of Tropical Medicine, Belgium (1)
Democratic Republic of the Congo (4) · Guinea (3) · Malaysia (1)
Elena Nicco (1) · Elena Nicco, MD (1) · Sharon Ng Shi Min (1) · Victor Kande Betu Kumeso, Dr (1) · Victor Kande Betu Kumeso, Dr. (1)