6 completed, 3 terminated, 1 unknown. 4 Not applicable, 4 Phase 1, 1 Early Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Completed 3, Terminated 1 |
| Phase 1 | 4 | Completed 2, Terminated 1, Unknown 1 |
| Early Phase 1 | 1 | Terminated 1 |
| Phase 2 | 1 | Completed 1 |
Follow 3,3'-diindolylmethane: new trials by email Literature Review of 3,3'-diindolylmethane trials Research Report on 3,3'-diindolylmethane
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Food Supplements on Food Intake and Gut Hormone Levels Lauric Acid, Perilla Oil and Diindolylmethane - Obesity, Endocrine; Obesity | Not applicable | Completed | Queen Mary University of London | 20 | 2019-02-22 | 2020-03-03 |
| 3,3'-Diindolylmethane in Patients With Systemic Lupus Erythematosus BR-DIM, Placebo - SLE | Phase 1 | Terminated | Northwell Health | 6 | 2016-01-01 | 2016-02-01 |
| A Nutritional Intervention to Decrease Breast Density Among Female BRCA (BReast CAncer Susceptibility Gene) Carriers DIM-Avail 100mg - BRCA1 Gene Mutation, BRCA2 Gene Mutation | Not applicable | Completed | Rabin Medical Center | 23 | 2014-11-11 | 2020-11-12 |
| Diindolylmethane in Treating Patients With Breast Cancer diindolylmethane, placebo - Stage IA Breast Cancer, Stage IB Breast Cancer | Not applicable | Completed | University of Arizona | 144 | 2011-02-01 | 2017-11-06 |
| Diindolylmethane in Treating Patients With Stage I or Stage II Prostate Cancer Undergoing Radical Prostatectomy B-Dim, Radical Prosatectomy - Prostate Cancer | Phase 2 | Completed | Barbara Ann Karmanos Cancer Institute | 41 | 2009-08-01 | 2018-03-19 |
| The Potential for Oral Diindolylmethane (DIM) Supplementation to Increase the Production of the BRCA1 Protein in BRCA1 Mutation Carriers Diindolylmethane (DIM) - Breast Cancer | Phase 1 | Unknown | Women's College Hospital | 300 | 2009-07-01 | 2009-12-01 |
| New Therapy of Laryngeal Papilloma In Children diindolylmethane (DIM), 585 nm pulsed dye laser - Papilloma | Not applicable | Terminated | Boston University | 1 | 2007-09-01 | 2017-05-18 |
| Diindolylmethane in Treating Patients Undergoing Surgery for Stage I or Stage II Prostate Cancer diindolylmethane, placebo, therapeutic conventional surgery - Adenocarcinoma of the Prostate, Prostate Cancer | Phase 1 | Completed | National Cancer Institute (NCI) | 45 | 2007-02-01 | 2015-12-04 |
| DIM as a Treatment for Thyroid Disease Diindolylmethane (DIM) - Proliferative Thyroid Disease | Early Phase 1 | Terminated | The New York Eye & Ear Infirmary | 7 | 2006-11-01 | 2013-05-03 |
| Diindolylmethane in Preventing Cancer in Healthy Volunteers diindolylmethane, placebo, pharmacological study - Healthy, no Evidence of Disease | Phase 1 | Completed | National Cancer Institute (NCI) | 20 | 2004-04-01 | 2016-12-29 |
Breast Neoplasms (3) · Prostatic Neoplasms (2) · Obesity (1) · Papilloma (1) · Recurrence (1) · Thyroid Diseases (1)
National Cancer Institute (NCI) (2) · Barbara Ann Karmanos Cancer Institute (1) · Boston University (1) · Northwell Health (1) · Queen Mary University of London (1) · Rabin Medical Center (1) · The New York Eye & Ear Infirmary (1) · University of Arizona (1) · Women's College Hospital (1)
United States (6) · Canada (1) · Israel (1) · United Kingdom (1)
Aryeh Hurwitz (1) · Cynthia Thomson (1) · David Margel, MD, PhD (1) · Elisabeth I. Heath, MD (1) · Jason Gee (1) · Madusha Peiris, PhD (1) · Richard Furie, MD (1) · Rinat Yerushalmi, MD (1) · Steven A Narod, MD (1) · Stimson P. Schantz, MD (1) · Zhi Wang, MD (1)
N01CN35008 (1), N01CN35153 (1), P30CA022453 (1), R01CA149417 (1), R01DC008287 (1)